女性细菌性阴道病的流行病学调查及阴道分泌物检测结果分析  

Epidemiological Investigation on Bacterial Vaginitis and Test Results of Vaginal Secretions in the Females

作　　者：黄晓宇 李桂梅 李华维 HUANG Xiaoyu;LI Guimei;LI Huawei(The Sixth People's Hospital of Huizhou City,Guangdong Province,Huizhou 516211,China)

机构地区：[1]广东省惠州市第六人民医院,惠州516211

出　　处：《宁夏医科大学学报》2021年第4期377-381,共5页Journal of Ningxia Medical University

基　　金：惠州市科技计划项目(20190406)。

摘　　要：目的分析女性细菌性阴道病的流行病学调查及阴道分泌物检测结果。方法收集2017年5月至2019年6月我院收治的82例细菌性阴道病患者作为细菌性阴道病组,另外选取阴道分泌物检查正常的女性76例作为正常组,分析导致细菌性阴道病发生的影响因素,统计细菌性阴道病组患者阴道分泌物病原菌分布与耐药性。结果单因素分析显示,不同文化程度、阴道炎认知程度、个人卫生情况、避孕措施的患者细菌性阴道病的发生率差异均有统计学意义(P均<0.05);多因素分析显示阴道炎认知程度差、个人卫生情况差、无避孕措施是细菌性阴道病发生的危险因素。通过细菌、真菌培养对细菌性阴道病组患者的阴道分泌物进行检测,82例细菌性阴道病患者共检出病原体136株,其中革兰阳性球菌71株、革兰阴性球菌58株、真菌7株;金黄色葡萄球菌、表皮葡萄球菌、腐生葡萄球菌、大肠埃希菌、铜绿假单胞菌是细菌性阴道病患者阴道分泌物中的主要病原菌。结论女性细菌性阴道病的发生与阴道炎认知程度差、个人卫生情况差、无避孕措施密切相关,应根据阴道分泌物病原菌及药敏检测对症治疗。Objective To analyze epidemiological investigation on bacterial vaginitis(BV)and test results of vaginal secretions in the females.Methods A retrospective collection was performed on case data of 82 BV patients who admitted to the hospital from May 2017 to June 2019,and they were enrolled as BV group.Another 76 normal women in vaginal secretions examination were enrolled as normal group.The risk factors which lead to BV were analyzed.The pathogens distribution of vaginal secretions and drug resistance in BV patients were statistically analyzed.Results Univariate analysis showed that there were significant differences in incidence of BV among patients with different educational level,vaginitis cognition degree,personal hygiene and contraceptive measures(P all<0.05).Multivariate analysis showed that poor vaginitis cognition degree,poor personal hygiene and lack of contraceptive measures were independent risk factors for occurrence of BV.The vaginal secretions of patients in BV group were detected by culture of bacteria and fungi.Among 82 BV patients,there were 136 strains of pathogens detected out,including 71 strains of Gram-positive cocci,58 strains of Gram-negative cocci and 7 strains of fungi.Among them,Staphylococcus aureus,Staphylococcus epidermidis,Staphylococcus saprophyticus,Escherichia coli and Pseudomonas aeruginosa were the main pathogens in vaginal secretions of BV patients.Conclusion The occurrence of BV in the females is closely related to poor vaginitis cognition degree,poor personal hygiene and lack of contraceptive measures.The symptomatic treatment should be conducted according to pathogens of vaginal secretions and drug sensitivity test.

关 键 词：细菌性阴道病 流行病学调查 支原体检测 衣原体检测 

分 类 号：R711.31[医药卫生—妇产科学]