3D打印生物陶瓷功能改进的研究进展  

Recent Development on Function Improvements of 3D Printed Bioceramics

作　　者：喻小鹏 吴成铁[1] YU Xiaopeng;WU Chengtie(State Key Laboratory of High Performance Ceramics and Superfine Microstructure,Shanghai Institute of Ceramics,Chinese Academy of Sciences,Shanghai 200050,China)

机构地区：[1]中国科学院上海硅酸盐研究所,高性能陶瓷和超微结构国家重点实验室,上海200050

出　　处：《硅酸盐学报》2021年第5期829-843,共15页Journal of The Chinese Ceramic Society

基　　金：国家重点研发计划(2018YFC1105201);国家自然科学基金(51761135103);上海市科委(20442420300);中国科学院交叉团队(JCTD-2018-13)。

摘　　要：临床上骨缺损的治疗方案虽然具有一定的治疗效果,但也存在不可忽视的局限性。生物陶瓷支架作为最有前景的解决方案被广泛研究。传统的生物陶瓷支架能在一定程度上修复骨缺损,但仍有许多不足。本综述简要归纳了制备多孔生物陶瓷支架的3D打印技术的原理及特点,然后重点介绍了3D打印生物陶瓷支架涉及的微量元素掺杂、功能性表面修饰、多孔结构的优化、微/纳米结构及仿生结构的构建等改进策略的最新进展,最后讨论了3D打印生物陶瓷面临的挑战及应用前景。Although the clinical bone defect treatments have certain therapeutic effects,they have unneglectable limitations.As a promising solution,bioceramic scaffolds are widely investigated.Conventional bioceramic scaffolds can repair the bone defect to some extent,but they still have some shortcomings.This review briefly summarized the principle and characteristics of the 3D printing techniques for the fabrication of the porous bioceramic scaffolds and highlighted the recent development on various improvement strategies for 3D-printed bioceramics,including doping trace elements,functional surface modification,optimization of the porous structure,construction of micro-/nano-structure and biomimetic structure.In addition,the challenges and application prospects of 3D printing of bioceramics were also discussed.

关 键 词：三维(3D)打印 生物陶瓷支架 表面修饰 微/纳米结构 仿生结构 

分 类 号：TQ175[化学工程—硅酸盐工业]