紫杉醇药物涂层球囊治疗股腘动脉硬化闭塞症的短期疗效  

Short-term efficacy of paclitaxel coated balloon in femoropopliteal arteriosclerosis

作　　者：尹月蕾 王坤[1] 王宾[1] 于剑 王辉[1] 史作磊[1] 李光新[1] Yin Yuelei;Wang Kun;Wang Bin;Yu Jian;Wang Hui;Shi Zuolei;Li Guangxin(Department of General Surgery,the First Affiliated Hospital of Shandong First Medical University&Shandong Provincial Qianfoshan Hospital,Ji'nan 250014,Shandong,China)

机构地区：[1]山东第一医科大学第一附属医院(山东省千佛山医院)普通外科学,山东济南250014

出　　处：《血管与腔内血管外科杂志》2021年第1期19-22,共4页Journal of Vascular and Endovascular Surgery

摘　　要：目的紫杉醇药物涂层球囊治疗股腘动脉硬化闭塞症的短期疗效。方法选取2019年1月至2020年6月山东第一医科大学第一附属医院(山东省千佛山医院)紫杉醇药物涂层球囊治疗股腘动脉硬化闭塞症患者26例(29条患肢)临床资料。所有患者术后第7天复查踝肱指数(ABI),术后1、3、6个月进行随访,统计靶血管一期通畅率、临床再干预率、ABI和截肢发生率。结果术后1、3、6个月,血管超声显示血管一期通畅率分别为100%、100%和93.10%(27/29);临床再干预率分别为0%、0%和3.45%(1/29);术后6个月截肢发生率和病死率均为0%。术前、术后第7天及术后1、3、6个月ABI比较,差异有统计学意义(P<0.01),术后第7天及术后1、3、6个月ABI均高于术前且术后第7天ABI最高(P<0.01)。结论股腘动脉硬化闭塞症患者使用紫杉醇药物球囊扩张治疗可以获得良好的短期通畅率,且安全有效。Objective To evaluate the short-term efficacy of paclitaxel coated balloon in the treatment of femoropopliteal arteriosclerosis.Method The clinical data of 26 patients(29 affected limbs)treated with paclitaxel coated balloon in the First Affiliated Hospital of Shandong First Medical University&Shandong Provincial Qianfoshan Hospital from January 2019 to June 2020 for femoropopliteal arteriosclerosis were selected.All patients were reexamined for ankle brachial index(ABI)on the 7 th day after surgery;follow-up was performed 1,3 and 6 months after surgery;the primary patency rate of target vessels,clinical re-intervention,ABI and amputation incidence were counted.Result 1,3 and 6 months after surgery,vascular ultrasound showed that the primary patency rates were 100%,100%and 93.10%(27/29),respectively,clinical re-intervention rates were 0%,0%and 3.45%(1/29),respectively.The incidence of amputation and fatality rate were 0%at 6 months postoperatively.ABI on the 7 th day,1,3 and 6 months after surgery were higher than those before surgery,with the highest ABI on the 7 th day after surgery(P<0.01).Conclusion The paclitaxel coated balloon dilation treatment in the femoropopliteal arteriosclerosis can achieve better short-term patency,which is safe and effective.

关 键 词：药物涂层球囊 股腘动脉 支架内再狭窄 踝肱指数 

分 类 号：R543[医药卫生—心血管疾病]