循证护理在预防放化疗病人口腔黏膜炎中应用效果的Meta分析  

Meta-analysis of application effect of evidence-based nursing on preventing oral mucositis in patients with chemoradiotherapy

作　　者：侯睿 岳延涛 王彬[1] 唐爱英 楚红枝 HOU Rui;YUE Yantao;WANG Bin;TANG Aiying;CHU Hongzhi(Xuchang Central Hospital Affiliated to Henan University of Science and Technology,Henan 461000 China)

机构地区：[1]河南科技大学附属许昌市中心医院,461000

出　　处：《全科护理》2021年第17期2314-2320,2361,共8页Chinese General Practice Nursing

摘　　要：目的:系统评价循证护理在放化疗病人口腔黏膜炎预防中的应用效果。方法:系统检索万方数据库、中国知网(CNKI)、维普中文科技期刊全文数据库(VIP)、中国生物医学文献数据库(CBM)、Cochrane Library、PubMed、Embase,检索时限均为建库起至2019年11月,收集有关循证护理在预防放化疗病人口腔黏膜炎中效果的随机对照试验,对符合纳入标准的临床研究进行资料提取,采用RevMan 5.3软件进行Meta分析。结果:共纳入14篇文献,合计1611例病人。Meta分析结果显示,循证护理组与常规护理组口腔黏膜炎总发生率[OR=0.33,95%CI(0.26,0.43),P<0.00001]、严重口腔黏膜炎发生率[OR=0.17,95%CI(0.10,0.27),P<0.00001]及护理满意度[OR=11.74,95%CI(3.50,39.43),P<0.0001]比较差异均有统计学意义。结论:循证护理可降低放化疗病人口腔黏膜炎的发生率,减轻口腔黏膜炎的严重程度,提高护理满意度。Objective:To systematically evaluate the application effect of evidence-based nursing in preventing the oral mucositis in patients with chemoradiotherapy.Methods:The databases of Wanfang,CNKI,VIP,CBM,Cochrane Library,PubMed,Embase were searched systematically.The retrieval time was from the establishment of the database to November 2019.Randomized controlled trials on the effect of evidence-based nursing in preventing the oral mucositis in patients with chemoradiotherapy were collected.Data were extracted from clinical studies that met the inclusion criteria,and Meta-analysis was conducted by using RevMan 5.3 software.Results:A total of 14 papers were included,involving 1611 patients.Results of Meta-analysis showed that there were statistical significance in the overall incidence of oral mucositis[OR=0.33,95%CI(0.26,0.43),P<0.00001],the incidence of severe oral mucositis[OR=0.17,95%CI(0.10,0.27),P<0.00001]and the nursing satisfaction[OR=11.74,95%CI(3.50,39.43),P<0.0001]between the evidence-based nursing group and the routine nursing group.Conclusions:Evidence-based nursing can reduce the incidence of oral mucositis,reduce the severity of oral mucositis,and improve nursing satisfaction.

关 键 词：循证护理 口腔黏膜炎 放疗 化疗 META分析 

分 类 号：R473.73[医药卫生—护理学]