应激性心肌病的研究进展  

Research progress of stress cardiomyopathy

作　　者：聂文畅 刘健[1] Nie Wenchang;Liu Jian(Department of Cardiology,Peking University People's Hospital,Beijing 100044,China)

机构地区：[1]北京大学人民医院心血管内科,北京100044

出　　处：《中国医学前沿杂志（电子版）》2021年第6期128-132,共5页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

基　　金：国家自然科学基金重点项目(11832003)

摘　　要：应激性心肌病(stress cardiomyopathy,SC),又称Tako-Tsubo综合征,最早于1990年由日本Sato等提出,是一种临床表现类似急性心肌梗死的左心室暂时性功能不全综合征,常发生于绝经期女性。SC急性期典型左心室造影呈颈窄、心尖球形膨隆的“tako-tsubo”(章鱼壶)状,多在1个月内恢复正常心室活动。SC触发事件多样并存在性别差异。目前多认为SC症状由交感神经过度兴奋引起冠状动脉微血管痉挛导致。较既往良性疾病的认知不同,SC急性期有较高的死亡率和并发症发生率。近年来确诊率的提高使SC备受关注。本文从流行病学、触发事件、病理生理学临床特征、诊断与鉴别诊断、治疗和预后方面对SC进行综述,以提高临床对该病的认识。Stress cardiomyopathy(SC),also known as Tako-Tsubo syndrome,was first proposed by Sato et al in Japan in 1990.It is a syndrome of temporary left ventricular insufficiency with clinical manifestations similar to acute myocardial infarction.It often occurs in menopausal women.In the acute stage,the typical left ventricular angiogram which was restored within 1 month showed a"tako-tsubo"shape with a narrow-necked apex and spherical bulge.The events triggered by SC are diverse and there are gender differences.At present,it is mostly believed that the symptoms of SC are caused by coronary microvasospasm due to sympathetic nerve overexcitation.Compared with previous perceptions of benign disease,SC has a higher mortality and complication rate in the acute stage.In recent years,the increase in the diagnosis rate has attracted attention to SC.The author reviews SC from epidemiology,trigger events,pathophysiology,clinical features,diagnosis and differential diagnosis,treatment and prognosis,in order to improve clinical understanding of the disease.

关 键 词：应激性心肌病 TAKO-TSUBO综合征 综述 

分 类 号：R542.2[医药卫生—心血管疾病]