睾丸显微取精结合卵质内单精子注射技术治疗非梗阻性无精子症的研究进展  

Research progress of the combination M-TESE and ICSI to treat NOA

作　　者：刘琳[1,2] 吕萌 李鑫濠 高文欣 马晓玲 LIU Lin;LYU Meng;LI Xinhao;GAO Wenxin;MA Xiaoling(The Reproductive Medicine Center,the First Hospital of Lanzhou University,Lanzhou 730000,Gansu,China;Key Laboratory of Reproductive Medicine and Embryo of Gansu Province,Lanzhou 730000,Gansu,China)

机构地区：[1]兰州大学第一医院生殖医学专科医院,兰州730000 [2]甘肃省生殖医学与胚胎重点实验室,兰州730000

出　　处：《中国性科学》2021年第5期4-7,共4页Chinese Journal of Human Sexuality

基　　金：甘肃省卫生行业科研计划项目(GSWSKY-2015-50);城关区科技计划项目(2019SHFZ0026)。

摘　　要：通过外科取精技术治疗非梗阻性无精子症(NOA)越来越多地应用于临床。随着外科取精术及卵质内单精子注射(ICSI)技术的日趋成熟,使得过去一直被认为是难以治疗的因生精功能障碍所致的NOA的治疗成为现实。现有的外科取精方法有多种,其中睾丸显微取精(M-TESE)被认为是治疗NOA所致不孕的优先选择,M-TESE结合ICSI对于NOA患者的治疗具有重要意义。本研究对现有的关于M-TESE结合ICSI治疗NOA患者的临床研究作一综述。Surgical sperm extraction for the treatment of non-obstructive azoospermia(NOA) has been increasingly applied in clinical practice. With the development of surgical sperm extraction and intracytoplasmic sperm injection(ICSI), the treatment of NOA due to spermatogenic dysfunction, which was previously considered to be difficult to treat, has become a reality. There are a variety of surgical sperm extraction methods, among which microscopic testicular sperm extraction(M-TESE) is considered to be the preferred choice for the treatment of NOA in infertile men, and M-TESE combined with ICSI is of great significance for the treatment of NOA patients. This article reviews the existing studies on the combination of M-TESE and ICSI in NOA patients.

关 键 词：睾丸显微取精 卵质内单精子注射 非梗阻性无精子症 男性不育 

分 类 号：R698.2[医药卫生—泌尿科学]