针刺治疗坐骨神经痛脑功能磁共振研究进展  

Progress of Study on fMRI in Sciatica Treated by Acupuncture

作　　者：李晓陵 马翠松 曹丹娜 王丰 蔡丽娜 竺柏年 王敬贤 孙旭晨 刘世平 Li Xiaoling(First Hospital Affiliated to Heilongjiang University of Chinese Medicine,Harbin 150040)

机构地区：[1]黑龙江中医药大学附属第一医院 [2]黑龙江中医药大学研究生院,黑龙江哈尔滨150040

出　　处：《黑龙江医药》2021年第3期497-499,共3页Heilongjiang Medicine journal

基　　金：国家自然科学基金面上项目(82074537,81973930);黑龙江省自然科学基金项目(LH2020H103,H2016081);哈尔滨市科技创新人才优秀学科带头人基金(2016RAXYJ096);教育部“春晖计划”(Z2009-1-15030);哈尔滨市科技创新人才专项资金项目(2017RAQXJ180);黑龙江省中医药科研项目(ZHY12-Z046);黑龙江省卫生厅科研课题(2012-346)。

摘　　要：针刺治疗坐骨神经痛在临床应用广泛,但其具体作用机制尚不确切。应用功能磁共振成像(Bold-fMRI)技术可以从影像学角度为针刺治疗坐骨神经疼痛提供客观理论依据,进而对针刺治疗坐骨神经痛的中枢机制进行分析与探索。本文对比针刺治疗坐骨神经痛任务态和静息态fMRI相关研究文献进行综述,发现针刺镇痛主要引起与痛觉辨识、疼痛认知、情绪调控有关脑区的神经元活动发生改变。以期为后续研究针刺镇痛的脑响应机制提供参考。Acupuncture is widely used in the treatment of sciatica,but its specific mechanism is not accurate.The application of Bold-fMRI can provide objective theoretical basis for acupuncture treatment of sciatic nerve pain from the perspective of imaging,and then analyze and explore the central mechanism of acupuncture in the treatment of sciatica.This paper compares the literature of fMRI in the task-state and rest-state of sciatica treated by acupuncture.It is found that acupuncture analgesia mainly causes the changes of neuron activity in brain area related to pain recognition,pain cognition and emotional regulation.

关 键 词：功能磁共振成像 针刺 坐骨神经痛 镇痛 

分 类 号：R246[医药卫生—针灸推拿学]