坏疽性脓皮病合并大动脉炎1例  

A Case of Pyoderma Gangrenosum Associated with Takayasu′s Arteritis

作　　者：经晶[1] 周聚普[2] 施辛[1] 陈玲玲 JING Jing;ZHOU Jupu;SHI Xin;CHEN Lingling(Department of Dermatology,Second Affiliated Hospital,Soochow University,Suzhou 215004,China;Department of Orthopedics,Second Affiliated Hospital,Soochow University,Suzhou 215004,China;Department of Dermatology,Suzhou Municipal Hospital,Suzhou 215002,China)

机构地区：[1]苏州大学附属第二医院皮肤科,江苏苏州215004 [2]苏州大学附属第二医院骨科,江苏苏州215004 [3]苏州市立医院本部皮肤科,江苏苏州215002

出　　处：《中国皮肤性病学杂志》2021年第6期661-665,共5页The Chinese Journal of Dermatovenereology

基　　金：苏州市第五批姑苏卫生人才培养项目(GSWS2019055)。

摘　　要：患者女,40岁,既往有大动脉炎病史10年,下腹、小腿反复发生坏死性溃疡,抗感染治疗效果不佳,积极清创、负压封闭引流(VSD)及灌洗后创面进行性扩大并伴有发热,活检病理符合嗜中性皮病,诊断为坏疽性脓皮病。应用大剂量糖皮质激素治疗后病情迅速得到控制并逐步缓解。A 40-year-old female who had been diagnosed with takayasu′s arteritis presented with recurrent and necrotizing ulcers on her leg and lower belly.She did not respond to treatment with several antibiotics and expanded rapidly with fever after active debridement.Skin biopsy revealed neutrophil infiltration of the dermis and subcutaneous tissue.High dose steroids were administered after the diagnosis of PG was established.The progress of disease was controlled soon and fully resolved finally.

关 键 词：坏疽性脓皮病 大动脉炎 坏死性溃疡 诊断 糖皮质激素 治疗 

分 类 号：R753[医药卫生—皮肤病学与性病学]