气候因素对流感影响的系统评价  

Effect of climate factors on influenza:A systematic review

作　　者：骆学勤[1] 谢晓虹[1] 罗征秀[1] LUO Xue-qin;XIE Xiao-hong;LUO Zheng-xiu(Department of Respiratory Disease,Children’s Hospital of Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,National Clinical Research Center for Child Heath and Disorders,China International Science and Technology Cooperation Base of Child Development and Critical Disorders,Chongqing Key Laboratory of Pediatrics,Chongqing400014,China)

机构地区：[1]重庆医科大学附属儿童医院呼吸中心儿童发育疾病研究教育部重点实验室国家儿童健康与疾病临床医学研究中心儿童发育重大疾病国家国际科技合作基地儿科学重庆市重点实验室,重庆400014

出　　处：《中国实用儿科杂志》2021年第5期376-381,共6页Chinese Journal of Practical Pediatrics

摘　　要：目的评估气候因素对流感的影响。方法通过检索Pubmed、Cochrane Library、Elsevier、万方数据库、中国知网(CNKI)从建库至2017年12月底的文献,依照纳入和排除标准筛选,采用STROBE量表对纳入的文献进行质量评价。使用Stata12.0软件行meta分析及描述性分析,评估气候因素与流感的活跃度和病死率的相关性。结果共检索到277篇文献,最终纳入21篇。纳入文献中气候因素均包含空气温度指标和湿度指标。热带地区:meta分析显示流感活跃度与湿度呈正相关[OR=1.16,95%CI:(1.12,1.21)],与气温呈负相关[OR=0.93,95%CI:(0.89,0.98)];流感病死率与湿度呈正相关。温带地区:85.7%的地区发现未分型流感的活跃度与湿度呈负相关,71.4%的地区与气温呈负相关;流感病死率与湿度呈负相关。寒带地区:流感活跃度与气温及湿度均呈负相关。结论流感的活跃度与气温呈负相关;热带地区的流感活跃度及病死率均与湿度呈正相关,温带地区则均呈负相关。Objective To evaluate the effect of climate factors on influenza.Methods Literatures were searched in Pubmed,Cochrane Library,Elsevier,Wanfang Data and CNKI database,and they were screened according to inclusion and exclusion criteria,then the quality was evaluated with STROBE.Meta analysis and descriptive analysis were conducted on eligible articles by Stata12.0 to evaluate the relationship between the climate factors and the activity and mortality of influenza.Results Twenty-one papers were selected out of 277 identified ones,and the climate factors in the included literatures include humidity and temperature.In tropical regions,humidity was found to be positively related to both influenza activity[OR=1.16,95%CI:(1.12,1.21)]and mortality,while temperature was only negatively related to influenza activity[OR=0.93,95%CI:(0.89,0.98)].In temperate regions,humidity was found to be negatively related to both influenza activity(85.7%of the research areas)and mortality(100%of the research areas),while temperature was only negatively related to influenza activity(71.4%of the research areas).In frigid regions,both humidity and temperature were found to be negatively related to influenza activity.Conclusion Humidity is positively related to influenza activity and mortality in tropical regions,and negatively related to them in temperate regions.Temperature is negatively related to influenza activity.

关 键 词：气候 流感 气温 湿度 系统评价 

分 类 号：R72[医药卫生—儿科]