慢性阻塞性肺疾病急性加重患者的药物治疗分析  

Analysis of drug treatment of patients with acute exacerbation of chronic obstructive pulmonary disease

作　　者：李博宇[1] 周梦 翟晓雨 于晓佳[1] 刘丽宏[1] LI Bo-yu;ZHOU Meng;ZHAI Xiao-yu;YU Xiao-Jia;LIU Li-hong(Department of Pharmacy,Beijing Chaoyang Hospital,Capital Medical University,Bejing 100020,China)

机构地区：[1]首都医科大学附属北京朝阳医院药事部,北京100020

出　　处：《中国临床药理学杂志》2021年第11期1433-1435,共3页The Chinese Journal of Clinical Pharmacology

摘　　要：临床药师参与慢性阻塞性肺疾病(COPD)急性加重患者的药物治疗过程,并依据相关指南提出用药建议和药学监护如下:抗感染药物的选择要根据经验及病原学证据综合考虑,同时应注意监护患者的肝肾功能;吸入糖皮质激素/长效抗毒蕈碱药/长效β2受体激动药的三联吸入治疗可改善COPD患者的肺功能、呼吸症状、健康状态并减少急性发作,但同时应指导患者正确使用吸入剂;住院的COPD急性加重患者宜在使用支气管扩张药的基础上,使用口服或静脉滴注的糖皮质激素治疗,以提高肺功能,并缩短住院时间。临床药师参与临床药物治疗过程可发挥药学专业优势,提升患者体验。Clinical pharmacists participated in the drug treatment process of chronic obstructive pulmonary disease(COPD) patients and put forward medication suggestions and pharmaceutical care according to the relevant guidelines as following: Anti-infective drugs should be considered according to the experience and etiological evidence, and the liver and kidney function of patients should be monitored. The triple inhalation therapy of inhaled corticosteroids/long-acting antimuscarinic antagonists/long-acting beta 2-agonists can improve the pulmonary function, respiratory symptoms, health status and reduce the acute attack of COPD patients. At the same time, we should teach patients to use inhalers correctly. The patients with acute exacerbation of COPD should use oral or intravenous glucocorticoids on the basis of bronchodilators, which can improve lung function and shorten the hospitalization time. Clinical pharmacists participating in the clinical drug treatment process can give full play to professional advantages and improve patients’ experience.

关 键 词：慢性阻塞性肺疾病 急性加重 抗感染 支气管扩张药 糖皮质激素 

分 类 号：R97[医药卫生—药品]