血浆置换联合血液透析滤过治疗产后溶血尿毒综合征三例疗效分析  

Analysis of the Efficacy of Plasma Exchange Combined with Hemodialysis on Three Cases of Postpartum Hemolytic Uremic Syndrome

作　　者：刘宏宇 赵秀宝[2] 刘伟[1] LIU Hong-yu;ZHAO Xiu-bao;LIU Wei(Department of Blood Transfusion,Tianjin First Central Hospital,Tianjin 300192,China;Intensive Care Unit,Tianjin First Central Hospital,Tianjin 300192,China)

机构地区：[1]天津市第一中心医院输血科,300192 [2]天津市第一中心医院重症医学科,300192

出　　处：《国际妇产科学杂志》2021年第3期264-267,共4页Journal of International Obstetrics and Gynecology

摘　　要：目的:探讨血浆置换(PE)联合血液透析滤过(HDF)对产后溶血尿毒综合征(PHUS)的治疗效果。方法:回顾性分析2017年9月—2019年9月天津市第一中心医院收治的3例采用PE联合HDF治疗的PHUS患者的临床资料,分析患者治疗前后临床症状及实验室检查结果的变化情况,并进行随访。结果:经过PE联合HDF治疗,患者临床症状均明显改善,血小板(PLT)、乳酸脱氢酶(LDH)恢复至正常水平,血红蛋白(Hb)及肾功能好转。随访2~4个月,2例患者恢复健康,1例因肾损伤严重遗留慢性肾功能不全。结论:PE联合HDF可作为PHUS的有效治疗手段。早期诊断并及时治疗有助于PHUS患者的病情恢复,对改善预后、保障母亲身体健康具有重要意义。Objective:To explore the efficacy of plasma exchange(PE)combined with hemodiafiltration(HDF)on postpartum hemolytic uremic syndrome(PHUS).Methods:The clinical data of 3 cases of PHUS patients treated with PE combined with HDF admitted to Tianjin First Central Hospital from September 2017 to September 2019 were retrospectively analyzed.The changes of clinical symptoms and laboratory examination results before and after treatment were compared and analyzed,and follow-up was conducted.Results:After PE combined with HDF,the clinical symptoms of the patients were significantly improved,platelets(PLT)and lactate dehydrogenase(LDH)returned to normal,hemoglobin(Hb)and renal function both improved.Follow-up for 2-4 months showed that 2 patients recovered,while 1 patient was left with chronic renal insufficiency due to severe renal injury.Conclusions:PE combined with HDF can be used as an effective treatment for PHUS.Early diagnosis and timely treatment are conducive to the recovery of PHUS patients,which is great significance to improve the prognosis and ensure mother′s health.

关 键 词：产褥期疾病 溶血尿毒症综合征 血浆置换 血液透析滤过 诊断 治疗结果 

分 类 号：R714.6[医药卫生—妇产科学]