含氮杂环化合物在Pd/C催化剂上催化加氢的研究  

Study on Catalytic Hydrogenation of Nitrogen Heterocyclic Compounds over Pd/C Catalyst

作　　者：陈丹 颜攀敦 张洁兰 李小虎 李岳锋 Chen Dan;Yan Pandun;Zhang Jielan;Li Xiaohu;Li Yuefeng(Xi’an Catalyst New Materials Co.,Ltd.,Shananxi Engineering Research Center of Noble Metal Catalyst,Xi’an 710201,China)

机构地区：[1]西安凯立新材料股份有限公司,陕西省贵金属催化剂工程研究中心,陕西西安710201

出　　处：《广东化工》2021年第9期71-72,113,共3页Guangdong Chemical Industry

摘　　要：本文以绿色催化加氢合成吲哚啉为研究目标,以5%Pd/C为催化剂,对吲哚催化加氢的反应工艺条件进行优化研究,考察了溶剂、反应温度、反应压力、反应时间、搅拌速度五个工艺条件对吲哚催化加氢性能的影响。结果表明,以5%Pd/C为催化剂,乙醇为溶剂、在90℃、1.2 MPa、600 rpm下反应30 min,原料转化率即可达到93%,吲哚啉选择性达100%。The green synthesis of indoline by catalytic hydrogenation was investigated.We focused on the process optimization of catalytic hydrogenation of indole with the catalyst of Pd/C,including the effects of solvent,reaction temperature,pressure,reaction time and stirring speed.The results showed that under the catalysis of 5%Pd/C catalyst,ethanol was used as solvent,when the reaction was carried out for 30 minutes under the conditions of 90℃,1.2 MPa and 600 rpm,the conversion of indole could reach 93%,and the selectivity of indoline could reach 100%.

关 键 词：吲哚啉合成 吲哚加氢 钯碳 工艺优化 

分 类 号：TQ[化学工程]