石蜡疗法治疗软组织损伤AO分型Ⅰ级临床研究  

Clinical Study on Paraffin Therapy for Soft Tissue Injury of GradeⅠBased on AO Classification

作　　者：余伟[1] 王军会[1] 郎伯旭[2] YU Wei;WANG Junhui;LANG Boxu

机构地区：[1]台州市博爱医院针灸推拿科,浙江台州318050 [2]台州市立医院针灸推拿科,浙江台州318050

出　　处：《新中医》2021年第10期67-71,共5页New Chinese Medicine

基　　金：浙江省台州市博爱医院院内课题。

摘　　要：目的:观察石蜡疗法治疗软组织损伤AO分型Ⅰ级的临床疗效及对应激因子、疼痛因子的影响。方法:选取软组织损伤AO分型Ⅰ级患者128例,按照随机数字表法分为观察组和对照组各64例。对照组给予祛风成骨胶囊、双氯芬酸钠联合治疗,观察组在对照组基础上给予蜡疗。比较2组治疗前后临床症状评分,检测治疗前后血液流变学指标、血清去甲肾上腺素(NE)、血管紧张素-2(AT-Ⅱ)、超氧化物歧化酶(SOD)、五羟色胺(5-HT)、P物质(SP)等水平,观察疼痛评分及不良反应发生情况。结果:与治疗前比较,治疗后2组肿胀、压痛、疼痛、瘀斑及功能障碍评分均减少(P<0.05);治疗后,观察组肿胀、压痛、疼痛、瘀斑及功能障碍评分均小于对照组(P<0.05)。与治疗前比较,治疗后2组血浆黏度、全血黏度低切、全血黏度高切、纤维蛋白原均降低(P<0.05);治疗后,观察组血浆黏度、全血黏度低切、全血黏度高切、纤维蛋白原均低于对照组(P<0.05)。与治疗前比较,治疗后2组血清NE、AT-Ⅱ水平均降低,SOD水平均升高(P<0.05);治疗后,观察组血清NE、AT-Ⅱ水平低于对照组,SOD水平高于对照组(P<0.05)。与治疗前比较,治疗后2组血清5-HT、SP水平及视觉模拟评分法(VAS)评分均降低(P<0.05);治疗后,观察组血清5-HT、SP水平及VAS评分均低于对照组(P<0.05)。观察组不良反应发生率为4.69%,对照组为1.56%,2组比较,差异无统计学意义(P>0.05)。结论:蜡疗可促进软组织损伤AO分型Ⅰ级患者局部血液、淋巴循环,改善临床症状及血液流变学指标,抑制炎性反应,缓解机体应激,减少生成疼痛因子,缓解疼痛,安全可靠。Objective:To observe the clinical effect of paraffin therapy for soft tissue injury of gradeⅠbased on AO classification and its effect on stress factors and pain factors.Methods:A total of 128 cases of patients with soft tissue injury of grade I based on AO classification were selected and divided into the observation group and the control group according to the random number table method,64 cases in each group.The control group was given Qufeng Chenggu capsules and diclofenac sodium,and the observation group was additionally given paraffin therapy based on the treatment of the control group.Clinical symptom scores before and after treatment were compared in the two groups.Hemorheology indexes as well as levels of norepinephrine(NE),angiotensin-2(AT-Ⅱ),superoxide dismutase(SOD),5-hydroxytryptamine(5-HT),and substance P(SP)in serum were detected before and after treatment.Pain score and incidence of adverse reactions were observed.Results:After treatment,scores of swelling,tenderness,pain,ecchymosis,and dysfunction in the two groups were decreased when compared with those before treatment(P<0.05);after treatment,the five scores in the observation group were lower than those in the control group(P<0.05).After treatment,plasma viscosity,whole blood viscosity at both high and low shear rates,and fibrinogen in the two groups were decreased when compared with those before treatment(P<0.05);after treatment,the four indexes in the observation group were lower than those in the control group(P<0.05).After treatment,levels of NE and AT-Ⅱin serum in the two groups were decreased when compared with those before treatment,and SOD levels were increased(P<0.05).After treatment,levels of NE and AT-Ⅱin serum in the observation group were lower than those in the control group,and SOD level was higher than that in the control group(P<0.05).After treatment,levels of 5-HT and SP in serum as well as scores of Visual Analogue Scale(VAS)in the two groups were decreased when compared with those before treatment(P<0.05);after trea

关 键 词：软组织损伤 AO分型Ⅰ级 石蜡疗法 祛风成骨胶囊 双氯芬酸钠 应激因子 疼痛因子 血液流变学指标 

分 类 号：R686[医药卫生—骨科学]