基于焦平面阵列的连续太赫兹波生物组织成像技术研究  

Continuous Terahertz Wave Biological Tissue Imaging Technology Based on Focal Plane Array

作　　者：王与烨[1,2] 蒋博周 徐德刚[1,2] 王国强 王一凡 姚建铨[1,2] Wang Yuye;Jiang Bozhou;Xu Degang;Wang Guoqiang;Wang Yifan;Yao Jianquan(School of Precision Instruments and Optoelectronics Engineering,Tianjin University,Tianjin 300072,China;Key Laboratory of Optoelectronics Information Technology(Ministry of Education),Tianjin University,Tianjin 300072,China)

机构地区：[1]天津大学精密仪器与光电子工程学院,天津300072 [2]天津大学光电信息技术教育部重点实验室,天津300072

出　　处：《光学学报》2021年第7期66-73,共8页Acta Optica Sinica

基　　金：国家重点基础研究发展计划(2015CB755403);国家自然科学基金(61775160,62011540006,61771332,U1837202)。

摘　　要：太赫兹焦平面成像是一种实用成像技术,具有快速成像、结构简单的特点,适用于生物组织的太赫兹波段成像。为此,搭建了一套反射式连续太赫兹波焦平面成像系统,对新鲜猪肉组织、大鼠脑组织和人脑胶质瘤组织进行成像。实验发现,通过添加成像窗口可以减少目标不平整表面的散射;同时,采用平场校正可以消除非均匀光照带来的影响。结果表明,反射式连续太赫兹波焦平面成像系统可用于对生物组织的实时成像,为生物组织的无标记快速成像提供了有效的技术手段。Terahertz focal plane imaging is a practical imaging technology with characteristics of rapid imaging and simple structure,which exhibits advantages for terahertz imaging of biological tissue.In this paper,a reflective continuous-wave terahertz focal plane imaging system is built to image fresh pork tissue,rat brain tissue,and human glioma tissue.It is found that the scattering of targets’uneven surface can be reduced by adding imaging window.Meanwhile,non-uniform illumination can be eliminated by flat field correction.The results show that reflective continuous-wave terahertz focal plane imaging system can be used for the real-time imaging of biological tissue,which provides an effective technical method for the rapid label-free imaging of biological tissue.

关 键 词：成像系统 太赫兹成像 焦平面阵列 反射式 实时 新鲜组织 

分 类 号：O436[机械工程—光学工程]