云南省保山市健康人群脑膜炎奈瑟菌带菌状况调查  

Investigation on carrying status of Neisseria meningitidis in healthy population in Baoshan City,Yunnan Province,China

作　　者：陈晨[1] 任远[2] 郭妮 郑月[2] 李育中[1] 唐聪[1] 谭银珍 李娇春 王学付 寸韡[1] 毕研伟[1] CHEN Chen;REN Yuan;GUO Ni;ZHENG Yue;LI Yu-zhong;TANG Cong;TAN Yin-zhen;LI Jiao-chun;WANG Xue-fu;CUN Wei;BI Yan-wei(Institute of Medical Biology,Chinese Academy of Medical Sciences,Kunming 650031,Yunnan Province,China;不详)

机构地区：[1]中国医学科学院北京协和医学院医学生物学研究所,云南昆明650031 [2]保山中医药高等专科学校,云南保山678000

出　　处：《中国生物制品学杂志》2021年第5期571-574,共4页Chinese Journal of Biologicals

基　　金：国家科技重大专项(2018ZX10101001)。

摘　　要：目的调查云南省保山市学校聚集的健康人群脑膜炎奈瑟菌(Neisseria meningitidis,Nm)带菌率,为分析保山市流行性脑脊髓膜炎(简称流脑)的发展趋势提供依据。方法在保山市18~22岁年龄段健康人群中采集1 076份咽拭子样本,常规分离培养鉴定及PCR鉴定和分型。结果 1 076份咽拭子样本中,分离出17株Nm,带菌率1.58%,其中B群14株、C群2株、X群1株。结论保山市存在校园聚集性的流脑无症状携带者,其中血清群以B群为主,其次为C群,并分离出1株X群Nm。Objective To investigate the carrying rate of Neisseria meningitidis(Nm) in healthy population gathered in schools in Baoshan City,Yunnan Province,China,and to provide a reference for analysis of the development trend of meningococcal meningitis in the city. Methods A total of 1 076 throat swab specimens were collected from the healthy people at ages of 18~22 years in Baoshan City,from which Nm was routinely separated,cultured and identified by PCR. Results Seventeen strains of Nm were isolated from 1 076 throat swab specimens,indicating a carrying rate of 1. 58%,among which 14 positive strains belonged to group B,2 to group C,and 1 to group X. Conclusion There are asymptomatic carriers of meningococcal meningitis in the campus of Baoshan City,major of which were of group B,followed by group C,and a Nm of group X was isolated.

关 键 词：流行性脑脊髓膜炎 无症状携带者 脑膜炎奈瑟菌 血清群 PCR 

分 类 号：R515.2[医药卫生—内科学]