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作 者:曹晔文 曹炜[2] 王欣妍 许涛 李露 CAO Ye-wen;CAO Wei;WANG Xin-yan;XU Tao;LI Lu(Beijing University of Chinese Medicine,Beijing 100029,China;Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)
机构地区:[1]北京中医药大学,北京100029 [2]中国中医科学院广安门医院,北京100053
出 处:《中国中医基础医学杂志》2021年第5期846-849,共4页JOURNAL OF BASIC CHINESE MEDICINE
基 金:国家重点研发计划资助(2018YFC1705500)-类风湿性关节炎中医分期防治方案的优化及循证评价研究。
摘 要:脂代谢异常是类风湿关节炎临床常见的并发症,其发病率高、早期症状隐匿,是诱发心脑血管疾病的重要危险因素,可能与患者长期使用抗风湿类药物、缺少运动以及类风湿关节炎本身炎症活动有关,二者相互影响,病程迁延,严重影响病人生活质量类。风湿关节炎伴脂代谢异常与痰瘀联系密切,痰瘀既是贯通疾病全程的病理产物,也是本病进一步加重的病理要素。痰瘀皆由水谷精微转化而来,由气机调控与营卫失和相关。曹炜教授认为营卫不和、痰瘀互结是本病发病的病理基础,并在多年的临床实践中,重视“痰瘀同治”的治疗原则以及当代人体质变化特点,用药时并重祛痰化瘀、清热祛湿、祛风通络、疏调气机、滋肾健脾等原则,注重用药时机,临床治疗效果颇佳。Abnormal lipid metabolism is a common complication of rheumatoid arthritis,which is a significant risk factor for cardiovascular and cerebrovascular diseases.It has a high morbidity and it is hard to be diagnosed.It may be related to the long-term use of antirheumatic drugs,lack of exercise and inflammatory activity of rheumatoid arthritis.The two diseases influence each other and affect the life quality of patients seriously.Rheumatoid arthritis with abnormal lipid metabolism is closely related to phlegm and blood stasis.Phlegm and blood stasis are not only pathological products throughout the whole course of the disease,but also pathological factors for the disease.Phlegm and blood stasis are all slightly transformed from cereal essence,regulated by Qi,and related to the disharmony of Ying and Wei.Professor Cao Wei believes that the discord between Ying and Wei,the accumulation of phlegm and blood stasis are the pathological basis of the disease.In clinical practice,we paid attention to the treatment principle of“remove the phlegm and blood stasis simultaneously”and the characteristics of physical changes of contemporary people.Some principles were important in clinical practice,which include expelling phlegm and removing blood stasis,clearing heat and dampness,dispelling wind and dredging collaterals,dredging qi-activity and nourishing kidney and spleen.The treatment effect was proved.
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