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作 者:字秋月 丁永丽 邓杨林[1] 陈新利[1] 吴晖[1] ZI Qiu-yue;DING Yong-li;DENG Yang-lin;CHEN Xin-Li;WU Hui(Department of Pharmacy,First Affiliated Hospital of Kunming Medical University,Kunming 650032,China)
机构地区:[1]昆明医科大学第一附属医院药剂科,昆明650032
出 处:《中国中医基础医学杂志》2021年第5期866-870,共5页JOURNAL OF BASIC CHINESE MEDICINE
基 金:云南省重大科技专项(生物医药)项目(2018ZF014)-彝、傣、瑶等特色民族药研究开发项目子课题1-治疗结节性甲状腺肿的雀梅藤医疗机构制剂研发;云南省卫生高层次人才培养项目(D-2017045)。
摘 要:文章从病名、病因病机、证候分型、治疗原则和用药规律等方面阐述中医药治疗结节性甲状腺肿的研究进展。结节性甲状腺肿是目前内分泌科的常见病,随着人们生活节奏的加快,工作压力的增加,结节性甲状腺肿患者逐渐增加。中医学认为结节性甲状腺肿属于中医学“瘿病”范畴,其主要病因包括饮食水土、情志内伤和体质因素,发病与肝、脾、肾密切相关,而气滞、痰凝、血瘀则为关键的病理因素。治疗应根据疾病的不同类型、不同阶段,抓住病机因病因人用药。中医药治疗结节性甲状腺肿临床疗效确切,优势明显,但缺乏统一的辨证论治分型标准,稳定有效的成方制剂相对欠缺以及具体药理作用、药效机制缺乏系统的论证,需加强相关经验的研究,以充分发挥其优势。The research progress of traditional Chinese medicine(TCM),including disease name,etiology and pathogenesis,symptom classification,therapeutic principle and prescription regularity,in treating nodular goiter was reviewed.Nodular goiter is a common clinical disease in department of endocrinology at present.As the increased of working pressure with the acceleration of social living standard,nodular goiter patients also increased.According to the clinical symptoms of TCM characteristics,nodular goiter belong to the category of“Ying disease”.The main etiology include diet,environment,emotion and physical factors,the onset of nodules goiter was closely related liver,spleen and kidney,among them qi stagnation,phlegm and blood stasis are the core of pathological factors.Individualized drug therapy is base on the difference of the patient's clinical manifestations,etiology and pathogenesis.The TCM treatment of nodules goiter has unique advantages,but the standard of syndrome differentiation has not unified.And it lacks stable and effective formulations and clearly pharmacological mechanism.Therefore,it is great significance to strengthen the research and development of Chinese medicine preparation and pharmacological mechanism.
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