IL-17和IL-35与多种疾病之间的研究进展  

Research Progress between IL-17 and IL-35 and Various Diseases

作　　者：王宇航 王为光[1] 赵悦荣 杜美霖[1] WANG Yuhang;WANG Weiguang;ZHAO Yuerong;DU Meilin(The First Affiliated Hospital of Jiamusi University,Jiamusi 154000,China)

机构地区：[1]佳木斯大学附属第一医院,黑龙江佳木斯154000 [2]黑龙江省佳木斯市中医医院

出　　处：《中国医学创新》2021年第14期180-184,共5页Medical Innovation of China

摘　　要：白细胞介素17(interleukin 17,IL-17)是由辅助性T细胞17(helper T cell 17,Th17)分泌具有细胞因子性质的蛋白,白细胞介素35(interleukin 35,IL-35)是IL-12家族的新成员可抑制Th17的分化及IL-17的分泌,从而发挥免疫抑制作用。目前研究认为,IL-17和IL-35参与人类各系统疾病的发生、发展,并将与各类疾病的关系进行综述。Interleukin 17 (IL-17) is a protein with cytokine properties secreted by T helper cell (Th17),interleukin 35 (IL-35) is a new member of the IL-12 family and can inhibit the differentiation of Th17 and the secretion of IL-17,thereby exerting an immunosuppressive effect.Current research believes that IL-17 and IL-35 are involved in the occurrence and development of various human diseases,and the relationship with various diseases will be reviewed.

关 键 词：白细胞介素17 白细胞介素35 自身免疫 肿瘤 

分 类 号：R392[医药卫生—免疫学]