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作 者:赖炽洪[1] 黄冰 罗涛 罗奕霖 LAI Chihong;HUANG Bing;LUO Tao;LUO Yilin(Guangdong Second Provincial General Hospital,Guangzhou 510317,China;不详)
出 处:《中国医学创新》2021年第15期156-159,共4页Medical Innovation of China
基 金:广东省医学科学技术研究基金项目(A2020073)。
摘 要:目的:观察对慢阻肺(COPD)合并肺动脉高压(PAH)患者行康复治疗的临床效果。方法:选取2018年4月-2020年4月广东省第二人民医院收治的120例慢阻肺合并肺动脉高血压患者,随机分为康复组和对照组,每组60例。对照组给予常规治疗,康复组在此基础上给予肺康复治疗(包括健康宣教、呼吸肌训练、运动锻炼、心理支持及营养指导)。两组均连续治疗6个月。比较两组患者治疗前后的肺功能指标(FEV1、FVC、FEV1/FVC%)、6 min最大步行距离(6MWD)、膈肌厚度分数(DTF)、气促指数及焦虑(SAS)和抑郁(SDS)量表评分。结果:治疗前,两组肺功能指标、6MWD、DTF、气促指数、SDS及SAS评分比较,差异均无统计学意义(P>0.05)。治疗后,两组肺功能指标、6MWD及DTF均高于治疗前,且康复组高于对照组(P<0.05);两组气促指数、SDS及SAS评分均低于治疗前,且康复组均低于对照组(P<0.05)。结论:对慢阻肺合并肺动脉高压患者行康复治疗可有效改善其肺功能及膈肌功能,且能减轻患者气促程度,同时可改良其抑郁、焦虑的负面情绪。Objective:To observe the clinical effect of pulmonary rehabilitation treatment of patients with chronic obstructive pulmonary disease complicated with pulmonary arterial hypertension.Method:A total of 120 patients with chronic obstructive pulmonary disease complicated with pulmonary arterial hypertension admitted to Guangdong Second Provincial General Hospital from April 2018 to April 2020 were randomly divided into rehabilitation group and control group,60 patients in each group.The control group received routine treatment,while the rehabilitation group received pulmonary rehabilitation treatment(including health education,respiratory muscle training,sports exercise,psychological support and nutritional guidance)on the basis of control group,and both two groups were treated for 6 months continuously.Lung function indexes(FEV1,FVC,FEV1/FVC%),6 min maximum walking distance(6 MWD),diaphragmatic thickness fraction(DTF),shortness of breath index,and anxiety(SAS)and depression(SDS)scale scores were compared between two groups before and after treatment.Result:Before treatment,there were no significant differences in lung function indexes,6 MWD,DTF,shortness of breath index,SDS and SAS scores between two groups(P>0.05).After treatment,lung function indexes,6 MWD and DTF of both groups were higher than before treatment,and the rehabilitation group were higher than those of the control group(P<0.05);the shortness of breath index,SDS and SAS scores of both groups were lower than before treatment,and the rehabilitation group were lower than those of the control group(P<0.05).Conclusion:Pulmonary rehabilitation treatment for patients with chronic obstructive pulmonary disease complicated with pulmonary arterial hypertension can not only improve their lung function and diaphragm function effectively and reduce the degree of shortness of breath,but also can improve the negative emotions of depression and anxiety.
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