肝移植术后巨细胞病毒感染的研究进展  

Research advances of cytomegalovirus infection after liver transplantation

作　　者：苏洋 丁佑铭[1] Su Yang;Ding Youming(Department of Hepatobiliary Endoscopic Surgery,Renmin Hospital of Wuhan University,Hubei Wuhan 430060,China)

机构地区：[1]武汉大学人民医院肝胆腔镜外科,湖北武汉430060

出　　处：《腹部外科》2021年第3期239-243,共5页Journal of Abdominal Surgery

基　　金：国家十二五科技支撑计划项目(2012BAD31B08)。

摘　　要：肝移植是目前治疗各种终末期肝病最有效的治疗手段。然而,巨细胞病毒(cytomegalovirus,CMV)感染作为肝移植术后常见的感染并发症之一,严重感染者可引起器官衰竭甚至死亡。熟悉CMV感染的危险因素,有效预防,早期诊断,积极治疗对于降低肝移植术后CMV感染的患病率和死亡率具有重要的意义。该文结合国内外最新研究报道对肝移植术后CMV感染的流行病学、危险因素、临床表现、诊断、防治及新兴治疗等方面进行了综述,以期减少病人术后排斥反应及术后移植物功能障碍的发生,提高病人术后生存率。Liver transplantation is the most effective treatment for all kinds of end-stage liver diseases.However,cytomegalovirus(CMV)infection is one of the most common complications after liver transplantation.Severe infection may lead to organ failure and even death.Understanding the risk factors of CMV infection,effective prevention,early diagnosis and aggressive interventions are vital for reducing the morbidity and mortality of CMV infection after liver transplantation.Epidemiological features,risk factors,clinical manifestations,diagnosis,prevention and treatment of CMV infection after liver transplantation were summarized with a goal of reducing postoperative rejection and graft dysfunction and improving postoperative survival rate of patients.

关 键 词：肝移植 巨细胞病毒 感染 术后 

分 类 号：R617[医药卫生—外科学]