原发性干燥综合征中医治疗经验荟萃  

Experience in traditional Chinese medicine treatment of primary Sj?gren’s syndrome

作　　者：张丽宁 姚传辉 罗静[2] 陶庆文[2] ZHANG Li-ning;YAO Chuan-hui;LUO Jing;TAO Qing-wen(Beijing University of Chinese Medicine,Beijing 100029,China;Department of Rheumatology of Traditional Chinese Medicine,China-Japan Friendship Hospital,Beijing Key Lab for Immune-mediated Inflammatory Disease,Beijing 100029,China)

机构地区：[1]北京中医药大学,北京100029 [2]中日友好医院中医风湿病科,免疫炎性疾病北京市重点实验室,北京100029

出　　处：《中华中医药杂志》2021年第5期2588-2592,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：阎小萍名医传承工作站(No.2015-SZ-C-57);中日友好医院院内课题(No.2018-156-K112)。

摘　　要：原发性干燥综合征(pSS)是一种慢性系统性自身免疫病,轻者口眼干,重者多系统受累,影响患者生活质量。本病目前尚无根治方法,中医药在改善pSS症状方面具有一定优势。文章通过检索中国期刊全文数据库、万方和维普数据库,筛选现代中医名家治疗pSS经验的文献,总结各医家的辨证经验、治法和常用方药等。本研究共纳入22篇文献,包括17位中医名家。现代中医名家治疗pSS多以"阴虚"或"虚毒瘀"立论,认为pSS最常见证候为阴虚燥热证,还常见气血两虚证和气滞血瘀证,病程中注重痰热瘀毒,治疗以养阴润燥为常法,治法中以养阴法使用最多,活血法次之,益气法和清热法并列第三,补血、化痰、解毒、温阳、理气等治法亦有使用。常用处方包括沙参麦冬汤、二至丸、生脉饮、杞菊地黄汤等,常用药物包括玄参、地黄、麦冬、杜仲、桑叶、香附、当归等。概而言之,现代中医名家普遍以"阴虚"或"虚毒瘀"立论治疗pSS,认为本病以阴虚燥热为常见证候,以养阴润燥为治疗常法,还常兼顾活血、益气、清热等,辨证准确,常获满意疗效。Primary Sj?gren’s syndrome(pSS)is a chronic systemic autoimmune disease with dry mouth and eyes,and severe cases may be accompanied by multiple system damage,which greatly affects the quality of life of patients.There is currently no cure for this disease.However,traditional Chinese medicine has certain advantages in improving the clinical symptoms of pSS.Literatures reporting experience of modern famous TCM doctors in treating pSS with full texts were included,and the dialectical experience,treatment and common used prescriptions were summarized in this article by searching China National Knowledge Infrastructure Databases(CNKI),Wanfang database and Chinese Scientific Journal Database(VIP).A total of 22 papers were included in the article,involving 17 famous TCM doctors.We find that most of the doctors focused on yin deficienc or deficiency,toxin and blood stasis in the treatment of pSS.They believed that the most common syndrome of pSS is yin deficiency with dryness-heat syndrome.The syndrome of qi and blood deficiency and the syndrome of qi stagnation and blood stasis are also common.Doctors should pay attention to phlegm,heat,blood stasis and toxicity during treatment.Most of doctors treat pSS with nourishing yin and moistening dryness.Among the therapies,the top three are the method of nourishing yin,promoting blood circulation,tonifying qi and clearing heat,while the methods of tonifying blood,resolving phlegm,relieving toxicity,warming yang and regulating qi are also used.Prescriptions which are commonly used include Shashen Maidong Decoction,Erzhi Pill,Shengmai Drink,Qiju Dihuang Decoction,etc..Herbs which are commonly used include Radix Scrophulariae,Radix Rehmanniae Recens,Radix Ophiopogonis,Cortex Eucommiae,Folium Mori,Rhizoma Cyperi,and Radix Angelicae Sinensis.Most of modern famous TCM doctors focused on yin deficiency or deficiency,toxin and blood stasis in the treatment of pSS.They generally believed that yin deficiency and heat is the most common syndrome of pSS,and nourishing yin and moistening

关 键 词：干燥综合征 中医 名医 经验 

分 类 号：R259[医药卫生—中西医结合]