Awakening Sleeping Beauty:Vinyl Esters for Macrolactonization  

作　　者：Qi Song Luyao Kong Lili Zhu Ran Hong Sha-Hua Huang 

机构地区：[1]School of Environmental and Chemical Engineering,Shanghai Institute of Technology,100 Haiquan Road,Shanghai,201418 China [2]CAS Key Laboratory of Synthetic Chemistry of Natural Substances,Center for Excellence in Molecular Synthesis,Shanghai Institute of Organic Chemistry(CAS),345 Lingling Road,Shanghai,200032,University of Chinese Academy of Sciences,19A Yuquan Road,Beijing,100049 China

出　　处：《Chinese Journal of Chemistry》2021年第4期1022-1024,共3页中国化学（英文版）

基　　金：the financial support from the Drug Innovation Major Project(No.2018ZX09711001-005);the Program of Shanghai Academic Research Leader(No.20XD1404700);the Key Research Program of Frontier Sciences(No.QYZDY-SSWSLH026);the Strategic Priority Research Program(No.XDB20000000)of the Chinese Academy of Sciences.

摘　　要：Macrolactones play a critical role in pharmaceuticals and agrochemicals.Numerous efforts have been devoted to developing synthetic methods for them.We highlighted a recent progress for building macrocycles(≥12-membered)via bench-stable vinyl ester(VE)intermediates,which have been underdeveloped for half century.

关 键 词：ACETYLENE Amide bond MACROLACTONIZATION Vinyl ester Ynamide 

分 类 号：O62[理学—有机化学]