内分泌激素与嗓音  

Hormones and voice

作　　者：庄佩耘[1] 刘昀逸 ZHUANG Peiyun;LIU Yunyi(Department of Voice,Xiamen University Zhongshan Hospital,Xiamen 361004,Fujian,China)

机构地区：[1]厦门大学附属中山医院嗓音科,福建厦门361004

出　　处：《山东大学耳鼻喉眼学报》2021年第3期5-9,共5页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：国家自然科学基金项目面上项目(81970871)。

摘　　要：内分泌系统与嗓音之间关系密切,激素水平波动会对发声系统的形态、结构产生影响,进而导致嗓音变化。喉部含大量的性激素和甲状腺激素受体,故性激素和甲状腺激素是导致嗓音障碍最重要的两种激素。性激素在人一生的不同阶段存在动态变化,会导致嗓音的改变,青春期和老年期变化最明显。嗓音训练治疗男声女调效果显著,极少需要手术。激素相关性药物对嗓音的影响显著,甚至不可逆,使用相关药物时需慎重。甲状腺激素降低引起的喉黏膜及声带水肿,极易被误诊为任克氏水肿,需注意鉴别诊断。耳鼻喉科医生应加深对嗓音障碍背后内分泌问题的认识,以做到更加清晰地识别。There is a close relationship between the endocrine system and the voice,and fluctuations in hormone levels have an impact on the shape and structure of the human vocal system,which in turn leads to voice changes.The larynx contains a large number of receptors for sex hormones and thyroid hormones,so sex hormones and thyroid hormones are the two most important hormones that cause voice disorders.Sex hormones have dynamic changes at different stages of human life,which can cause voice changes,which are most obvious in adolescence and old age.Mutational falsetto,also known as puberphonia,is very sensitive to voice training therapy,so it is necessary to be cautious when choosing surgical treatment.Furthermore,the hormone-related drugs has a significant and even irreversible impact on the voice,so caution should be used when using them.In addition,laryngeal mucosa and vocal cord edema caused by hypothyroidism can easily be misdiagnosed as Reinke?s edema,which requires attention to distinguish.Finally,otolaryngologists should deepen their understanding of the endocrine problems behind voice disorders in order to more clearly identify the primary disease.

关 键 词：内分泌 激素 嗓音障碍 男声女调 声带水肿 

分 类 号：R767.92[医药卫生—耳鼻咽喉科]