丝素蛋白/氨基氧化石墨烯复合水凝胶的制备及性能研究  

Preparation and Properties of Silk Fibroin/Aminated Graphene Oxide Polymeric Hydrogel

作　　者：朱燕祥 焦玉全 黄佳涔 李莉 彭晓佳 张鲁中[2] 赵亚红[2] Zhu Yanxiang;Jiao Yuquan;Huang Jiacen;Li Li;Peng Xiaojia;Zhang Luzhong;Zhao Yahong(Nantong Vocational College of Science & Technology,Nantong 226001,China;Key Laboratory of Neuroregeneration,Nantong University,Nantong 226001,China;School of Public Health,Nantong University,Nantong 226001,China)

机构地区：[1]南通科技职业学院,江苏南通226001 [2]南通大学神经再生重点实验室,江苏南通226001 [3]南通大学公共卫生学院,江苏南通226001

出　　处：《南京师大学报（自然科学版）》2021年第2期24-29,共6页Journal of Nanjing Normal University(Natural Science Edition)

基　　金：科技部国家重点研发计划资助项目(2018YFC1105604);国家自然科学基金资助项目(81701835).

摘　　要：本文采用京尼平交联方法,制备了不同氨基氧化石墨烯含量的丝素蛋白复合水凝胶.对该复合水凝胶的抗压力学性能、溶胀性、磷酸缓冲盐溶液(phosphate buffer saline,PBS)稳定性、电导率以及循环伏安曲线检测表明,氨基氧化石墨烯能够显著改进丝素蛋白复合水凝胶的弹性、PBS溶液中的稳定性以及导电性.该研究将促进丝素蛋白复合水凝胶在再生医学领域中的广泛应用.By approach of genipin cross-linking,the silk fibroin/aminated graphene oxide(NGO-SF)polymeric hydrogel that contains different concentration of aminated graphene oxide(NGO)was successfully prepared.Measurement of compressive resistance,water absorption,degradation in phosphate buffer saline(PBS),electrical conductivity,as well as cyclic voltammetry for the polymerized hydrogel,demonstrated that the application of NGO was able to improve the elasticity,stabilization in PBS and the conductivity of the material.This study will promote the application of the composite hydrogel based on silk fibroin in the field of regenerative medicine.

关 键 词：丝素蛋白 氨基氧化石墨烯 水凝胶 导电性 力学性能 

分 类 号：O59[理学—应用物理] R318.08[理学—物理]