全胃切除术后草铵膦中毒一例  

A case of glufosinate-ammonium poisoning in a patient with total gastrectomy

作　　者：张晓敏 孙昊 张劲松 胡德亮 张芹 Zhang Xiaomin;Sun Hao;Zhang Jinsong;Hu Deliang;Zhang Qin(Department of Emergency,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学第一附属医院急诊医学科,210029

出　　处：《中华劳动卫生职业病杂志》2021年第5期366-367,共2页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：江苏省医学创新团队(CXTDA2017007)。

摘　　要：目的分析1例全胃切除后草铵膦中毒患者的诊疗过程。方法对2020年8月南京医科大学第一附属医院收治的1例全胃切除患者口服草铵膦中毒的临床资料进行综合分析。结果患者在全胃切除情况下口服草铵膦约200 ml入院,中毒6.5 h后血浆草铵膦浓度为816.8 ng/ml。经促毒物排泄、补液、抗感染、保护重要脏器等对症治疗后,患者好转出院。结论全胃切除的草铵膦中毒患者临床表现仍以神经系统症状为主,且有延迟效应。全胃切除是否会影响毒物分布及毒性效应,仍需进一步探索。Objective To analyze the diagnosis and treatment of a patient with glufosinate-ammonium poisoning after total gastrectomy.Methods The clinical data of a patient with oral glufosinate-ammonium poisoning after total gastrectomy in the First Affiliated Hospital of Nanjing Medical University in August 2020 were analyzed.Results After total gastrectomy,the patient took about 200 ml of glufosinate-ammonium orally,and the plasma glufosinate-ammonium concentration was 816.8 ng/ml 6.5 h after poisoning.After symptomatic treatment such as promoting poison excretion,rehydration,anti infection and protecting important organs,the patient improved and discharged.Conclusion The clinical manifestations of patients with glufosinate-ammonium poisoning after total gastrectomy are still mainly neurological symptoms,with delayed effect.Whether total gastrectomy will affect the distribution and toxic effect of the poison still needs further exploration.

关 键 词：农药 草铵膦 全胃切除 急性中毒 毒物动力学 毒物检测 

分 类 号：R656.61[医药卫生—外科学] R595.4[医药卫生—临床医学]