耐火陶瓷纤维对人体呼吸系统损伤的研究进展  

Research progress of refractory ceramic fiber's damage to human respiratory system

作　　者：杨思雯 朱晓俊 马文军[1] Yang Siwen;Zhu Xiaojun;Ma Wenjun(School of Public Health,Peking University,Beijing 100191,China;Occupational Safety and Health Research Center of National Health Commission,Beijing 102308,China)

机构地区：[1]北京大学公共卫生学院,100191 [2]国家卫生健康委职业安全卫生研究中心,102308

出　　处：《中华劳动卫生职业病杂志》2021年第5期393-396,共4页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：北京市自然科学基金资助项目(7192137)。

摘　　要：耐火陶瓷纤维(RCFs)作为石棉的主要替代品,因其耐高温和良好的绝热性被广泛使用。在生产和使用场所空气中的RCFs属于可吸入纤维,易在肺部发生沉积。多项流行病学和毒理学研究表明RCFs与肺部疾病的发生有关。本文从RCFs致胸膜增厚、肺纤维化、肺功能损伤和肿瘤及遗传损伤角度进行综述,并对RCFs对呼吸系统损伤相关研究的前景加以展望。Refractory ceramic fibers(RCFs),as the main substitute for asbestos,are widely used because of their high temperature resistance and good thermal insulation.In the air of its production and use places,RCFs are inhalable fibers that are easy to deposit in the lungs.The results of a number of epidemiological studies and a variety of toxicological methods have shown that RCFs are related to the occurrence of lung diseases.This article reviews the four aspects of RCFs-induced pleural thickening,pulmonary fibrosis,lung function damage,tumor and genetic damage,and looks forward to the prospects of RCFs on respiratory system damage related research.

关 键 词：呼吸系统 纤维 陶瓷纤维 胸膜增厚 肺纤维化 肺功能 肿瘤 遗传损伤 

分 类 号：R56[医药卫生—呼吸系统]