论中药剂量对药物升降作用的影响  

The influence of dosage on the ascending-descending effects of Chinese medicine

作　　者：时浩洋 马铭泽 孙肇阳 吕桂娇 孟静岩[1] SHI Haoyang;MA Mingze;SUN Zhaoyang;LYU Guijiao;MENG Jingyan(College of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)

机构地区：[1]天津中医药大学中医学院,天津301617

出　　处：《天津中医药大学学报》2021年第3期301-304,共4页Journal of Tianjin University of Traditional Chinese Medicine

基　　金：国家科技部重点基础研究发展计划(973计划)项目(2013CB531701)。

摘　　要：药性升降源于自然现象升降,基于人体气机升降,本质与两者相通,其本身阴与阳的比例决定了药物的升降作用。气味厚薄是古人通过口尝鼻嗅总结出的气或味中浓厚或淡薄的偏性,是气味对药性升降影响的间接归纳,气厚者具有升的趋势,气薄者升的趋势较弱,味厚者具有降的趋势,味薄者降的趋势较弱。据此,在运用时加大用量提高其药剂的浓度,虽天然药物本身味薄,但在形成方剂时已被转化成了味厚之品,则可能具有更强的降的趋势。气之厚薄也是同理,加大剂量会使本身气薄的药物转化为气厚之品,加强其升的性质。利用电子鼻和电子舌技术可以客观化不同剂量药物的气味属性,分析与其升降作用的关联性,验证基于《黄帝内经》理论提出的剂量对药物升降作用影响原理的可靠与否及适用范围。The ascending and descending effects of medicine originate from the law of nature,and correspond to ascending and descending of human qi.As a result,what they have in common is the ascending and descending action determined by the proportion of yin and yang.The property of qi and flavor is characteristic of thick or weak in the qi and flavor which summarized by the ancients through tasting and smelling,which indirectly summarized the influence of dosage on the ascending-descending effects.The thick qi has a ascending trend,the slighter one has a weak ascending trend;the thick flavor has a descending trend,and the slighter one has a weak descending trend.According to the theory,adding the dosages can increase the concentration of the medicine,and it can also transformed into a thick taste product,it may have a stronger descending trend although the medicine has a weak taste.The property of qi is has the same principle.Adding the dosages will transform the medicine which with weak qi into the products which with thick qi and can also strengthen its ascending trend.By using electronic nose and electronic tongue technology,the qi and flavor of different doses of drugs can be objectively analyzed,and the relationship between the qi and flavor and the ascending and descending effects of drugs can be analyzed,thus verify the reliability and scope of application of the principle of the influence of dosage on the ascending-descending effects based on the theory of Inner Canon of the Yellow Emperor.

关 键 词：药性理论 气味厚薄 气机升降 

分 类 号：R285.1[医药卫生—中药学]