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作 者:张腊 ZHANG La(Department of Clinical Laboratory,Jinzhou First People's Hospital,Dalian 116000,China)
机构地区:[1]大连市金州区第一人民医院检验科,辽宁大连116000
出 处:《中国医药指南》2021年第13期74-75,共2页Guide of China Medicine
摘 要:目的探讨小儿支原体肺炎患者采取咽拭子培养及药敏的意义分析。方法选取2017年1月至2019年1月在辽宁省金州区第一人民医院就诊的200例小儿支原体肺炎患者,通过咽拭子采集分泌物,对标本进行肺炎支原体(MP)培养及药物敏感试验。结果在药物敏感试验中,MP对阿奇霉素以及左氧氟沙星、克拉霉素以及加替沙星和司帕沙星的敏感率较高,对红霉素、罗红霉素、乙酰螺旋霉素和克林霉素有较高的耐药率,差异具有统计学意义(P<0.05)。结论咽拭子培养对MP检出率较高,在药物敏感试验中MP对常用抗生素耐药性较高,对阿奇霉素的耐药性低,这对于小儿支原体肺炎的鉴别诊断和抗生素的选择具有指导作用。Objective To explore the significance of pharyngeal swab culture and drug sensitivity analysis in children with mycoplasma pneumonia.Methods Two hundred cases of pediatric mycoplasma pneumonia were selected from January 2017 to January 2019 in the First People’s Hospital of Jinzhou District.The samples were cultured with mycoplasma pneumoniae(MP)and tested for drug sensitivity.Results In the drug sensitivity test,MP had higher sensitivity rates to azithromycin,levofloxacin,clarithromycin,gatifloxacin and sparfloxacin,and higher resistance rates to erythromycin,roxithromycin,acetylspiramycin and clindamycin,with statistically significant differences(P<0.05).Conclusion Pharyngeal swab culture has a higher MP detection rate,higher MP resistance to common antibiotics in drug sensitivity test,and lower MP resistance to azithromycin,which has a guiding role in the differential diagnosis of mycoplasma pneumonia in children and the selection of antibiotics.
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