自拟补肾汤联合西药治疗慢性肾小球肾炎的临床疗效观察  

Clinical Observation of Self-made Bushen Decoction Combined with Western Medicine in the Treatment of Chronic Glomerulonephritis

作　　者：罗昭强 何隆[2] LUO Zhaoqiang;HE Long(Department of Nephrology,Ya'an Hospital of Traditional Chinese Medicine,Ya'an 625000,China;Sichuan Provincial Hospital of Traditional Chinese Medicine,Chengdu 610075,China)

机构地区：[1]雅安市中医医院肾病科,四川雅安625000 [2]四川省中医院,四川成都610075

出　　处：《中国医药指南》2021年第13期123-125,共3页Guide of China Medicine

摘　　要：目的观察自拟补肾汤联合西药治疗慢性肾小球肾炎的临床疗效。方法将68例慢性肾炎患者随机分为观察组与对照组,每组各34例,对照组患者采用常规西药治疗;观察组患者在对照组基础上加用自拟补肾汤治疗,两组用药时间均为4周,比较两组治疗结束后的临床疗效、治疗前后的肾功能指标以及血清炎性因子指标。结果观察组临床总有效率为91.18%,显著优于对照组的73.53%(P<0.05);治疗后,观察组24 h尿蛋白定量、Scr、BUN以及TNF-α、IL-6水平均低于治疗前和对照组,差异均有统计学意义(P<0.05)。结论自拟补肾汤联合西药治疗慢性肾小球肾炎疗效确切,值得在临床推广使用。Objective To observe the clinical efficacy of self-made bushen decoction combined with western medicine in the treatment of chronic glomerulonephritis.Methods Sixty-eight patients with chronic nephritis were randomly divided into observation group(n=34)and control group(n=34).The control group was treated with routine western medicine,and on the basis of this,the observation group was treated with self-made bushen decoction.The medication time of the two groups was 4 weeks.The clinical efficacy,renal function indexes before and after treatment and serum inflammatory factor indexes were compared between the two groups after treatment.Results The clinical total effective rate of the observation group was 91.18%,which was significantly better than 73.53%of the control group,there were significant differences in two groups(P<0.05);after treatment,24 hours urinary protein,Scr,BUN,TNF-α,IL-6 levels in the observation groups were lower than those before treatment and the control group,there were significant differences(P<0.05).Conclusion The self-made bushen decoction combined with western medicine in the treatment of chronic glomerulonephritis has exact curative effect,which is worthy of clinical application.

关 键 词：慢性肾小球肾炎 自拟补肾汤 肾功能 疗效观察 

分 类 号：R692.3+1[医药卫生—泌尿科学]