薤白组合制剂对早期尿毒症患者肾功能逆转及尿量增多临床效果分析  

Clinical Effects of Allium Macrostemon And Other Traditional Chinese Medicines on Renal Function Reversal and Urine Volume Increase in Early Uremia

作　　者：温文斌 亢雪峰 郭辽朵 王亿甲 郭毅 宋蓉蓉 王小其 马添宏 WEN Wen-bin;KANG Xue-feng;GUO Liao-duo(Yichuan Hospital of Traditional Chinese Medicine,Yichuan,Henan,471300,China)

机构地区：[1]河南省伊川县中医院,河南伊川471300

出　　处：《中国初级卫生保健》2021年第6期79-81,共3页Chinese Primary Health Care

基　　金：伊川县科技局、财政局2016年科技计划项目(2016-21)。

摘　　要：目的:观察薤白组合制剂对早期尿毒症肾功能逆转及尿量增多的治疗效果。方法:选取120例早期慢性肾功能衰竭及尿毒症患者,分为对照组和治疗组,每组60例,两组入组标准为慢性肾功能衰竭患者或进入透析治疗有尿量患者,对照组给予控制血压(硝苯地平缓释片:陕西步长高新制药有限公司,国药准字H61023583,10 mg Tid Po;贝那普利片:诺华制药,国药准字H20000292,10 mg Bid Po;倍他乐克片:阿斯利康药业中国有限公司,国药准字1808A26,25 mg BidPo);纠正贫血:促红素(上海凯茂,国药准字S19991024,3 000 u/次,2次/周);利尿:呋塞米片(江苏亚邦爱普森药业有限公司,国药准字H32021428,20 mg Tid Po)等对症支持治疗。治疗组在对照组的基础上加用薤白组合制剂,0.5 g/粒, 2粒/次,3次/d,口服,并对两组患者血尿素氮(BUN)、肌酐(Scr)及24 h尿量临床疗效进行比较。结果:治疗后治疗组与对照组相比肾功能及24 h尿量有改善,差异有统计学意义(P<0.05)。结论:对于慢性肾功能衰竭尿毒症患者采用控制血压、改善纠正肾性贫血及合理使用利尿剂等对症支持治疗的同时,加用薤白组合制剂可改善患者肾功能、增加尿量。OBJECTIVE To observe the therapeutic effects of Allium macrostemon and other traditional Chinese medicines on the reversal of renal function and increased urine output in early uremia. METHODS 120 patients with uremia in chronic renal failure were selected and were randomly divided into two groups of 60 patients each. The control group was uniformly treated with conventional dialysis three times a week and given blood pressure control(NIFEDIPINE SUSTAINED-RELEASE TABLETS: Shanxi Buchang High-Tech Pharmaceutical Co Ltd, Standard Chinese Medicine H61023583, 10 mg Tid Po;BENAZEPRIL HYDROCHLORIDE TABLETS: Novartis Pharmaceuticals, Standard Chinese Medicine H20000292, 10 mg Bid Po;METOPROLOL TABLETS: AstraZeneca Pharmaceuticals China Ltd, Standard Chinese medicine 1808 A26, 25 mg Bid Po);Correction of anaemia(Recombinant Human Erythropoietin for injection: Shanghai Kaimao Biomedical Co Ltd, Standard Chinese Medicine S19991024, 3000 u/dose);Diuresis: FUROSENIDE TABLETS(Jiangsu Yabang Epsom Pharmaceutical Co Ltd, Standard Chinese Medicine H32021428, 20 mg Tid Po) and other symptomatic support treatment. The treatment group was treated with allium macrostemon and cordyceps capsule, 2 capsule per time, 3 times per day and the clinical effects of blood urea nitrogen(Bun), creatinine(SCR) and 24 h urine volume were compared between the two groups. RESULTS Renal function and 24 h urine volume were improved in the control group after treatment(P<0.05). Compared with the control group, renal function and 24 h urine volume were significantly improved in the treatment group. CONCLUSION In patients with chronic kidney failure uremia, symptomatic support such as control of blood pressure, correction of anemia, diuresis, etc. It was significant to add allium macrostemon and cordyceps capsule to improve renal function, increase urine volume and delay disease development.

关 键 词：薤白中药组合制剂 早期尿毒症 肾功能 尿量 

分 类 号：R197[医药卫生—卫生事业管理]