百合化学成分及药理活性研究进展  被引量:40

Advance in Research on Chemical Constituents and Pharmacological Activities of Lilium

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作  者:粟倩 吴萍[1,2] 夏伯候 李亚梅[1,2] 林艳 林丽美[1,2] 廖端芳 SU Qian;WU Ping;XIA Bo-hou;LI Ya-mei;LIN Yan;LIN Li-mei;LIAO Duan-fang(College of Pharmacy,Hunan University of Traditional Chinese Medicine,Changsha 410208,China;Key Laboratory for Quality Evaluation of Bulk Herbs of Hunan Province,Changsha 410208,China)

机构地区:[1]湖南中医药大学药学院,长沙410208 [2]湘产大宗药材品质评价湖南省重点实验室,长沙410208

出  处:《中国药学杂志》2021年第11期875-882,共8页Chinese Pharmaceutical Journal

基  金:湖南省杰出青年科学基金资助(2017JJ2013);教育厅优秀青年基金资助(17B198);长沙市科技局项目资助(KQ1801046,KQ1801041,KQ1804027)。

摘  要:本文主要综述了百合属的传统用法、化学成分和药理活性等方面的研究进展。已从百合中分离出甾体皂苷、酚酸、黄酮类化合物、生物碱、甾体糖生物碱及多糖等化合物。现代药理学研究表明,百合具有抗肿瘤、抗炎、抗氧化、增强免疫、降血糖、抗真菌及抗抑郁等作用,与这些功能相关的活性成分主要是甾体皂苷、酚酸和多糖。百合作为原国家卫生部首批药食同源品种之一,具有很高的开发利用价值,笔者为其进一步开发利用提供参考。This review mainly summarizes the advances in research on the traditional usage,chemical components and pharmacological functions of Lilium.A large number of steroidal saponins,phenolic acids,flavonoids,alkaloids,steroidal glycoalkaloids and polysaccharides have been isolated from the plants.Modern pharmacological studies have revealed that Lilium possess anti-tumor,anti-inflammatory,anti-oxidative,immunoregulatory,hypoglycemic functions,antimycotic and anti-depressive activities.The active components related to these functions are mainly steroidal saponins,phenolic acids and polysaccharides.As one of the first batch of medicine and food homologous varieties recognized by the Ministry of Health,Lilium has a very high development and utilization value,and this paper provides a reference for the further development and utilization of Lilium.

关 键 词:百合属 甾体皂苷 药理活性 

分 类 号:R284[医药卫生—中药学]

 

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