超声心动图左室压力-应变环评价正常成年人心肌做功  

Assessment of Myocardial Work in Healthy Adults By Echocardiographic Left Ventricular Pressure-strain Loop

作　　者：丁雪晏 李一丹[1] 蔡绮哲[1] 秦芸芸 李沅芝 王江涛 吕秀章[1] Ding Xueyan;Li Yidan;Cai Qizhe;Qin Yunyun;Li Yuanzhi;Wang Jiangtao;Lü Xiuzhang(Department of Echocardiography,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China;Department of Clinical Research,General Electrics Cardiovascular ultrasound,Beijing 100176,China)

机构地区：[1]首都医科大学附属北京朝阳医院心脏超声科,北京市100020 [2]通用电气医疗心血管超声临床科研部,北京市100176

出　　处：《中国超声医学杂志》2021年第6期655-658,共4页Chinese Journal of Ultrasound in Medicine

基　　金：北京市医院管理局临床技术创新项目(No.XMLX201827)。

摘　　要：目的应用超声心动图左室压力-应变环(PSL)评价正常成年人心肌做功,并探讨其影响因素。方法选取64例健康成人志愿者进行超声心动图检查。应用斑点追踪超声心动图(STE)测量受试者左心室整体长轴应变(GLS)、机械离散度(MD)。通过左室PSL评价心肌做功参数,包括心肌整体做功指数(GWI)、整体有效功(GCW)、整体无效功(GWW)、整体做功效率(GWE)。结果①女性GWI、GCW高于男性(P<0.05),GWW、GWE无差异;②多因素回归分析显示,GWI、GCW分别与收缩压(β=0.623,β=0.626,P<0.001)、GLS(β=0.401,β=0.36,P<0.001)、左心室射血分数(β=0.326,β=0.342,P<0.001)呈独立相关,GWW、GWE与MD独立相关(β=0.269,P=0.033,β=-0.364,P=0.003)。结论左室压力-应变环评价心肌做功可以反映左心室收缩功能及同步性且重复性良好,具有潜在的临床应用价值。Objective To evaluate myocardial work by echocardiographic left ventricular pressure-strain loop(PSL)in healthy adults and explore its affect factors.Methods 64 healthy volunteers were prospectively enrolled and received echocardiography.Speckle tracking echocardiography(STE)was used to measure global longitudinal strain(GLS)and mechanical dispersion(MD).The left ventricular myocardial work index was evaluated by left ventricular PSL,including global work index(GWI),global constructive work(GCW),global waste work(GWW),and global work efficiency(GWE).Results①GWI and GCW were higher in female than male(P<0.05),while GWW and GWE had no difference.②On multivariate analysis,GWI and GCW were independently correlated with systolic blood pressure(β=0.623,β=0.626,P<0.001),GLS(β=0.401,β=0.36,P<0.001)and left ventricular ejection fraction(β=0.326,β=0.342,P<0.001),while GWW and GWE were independently correlated with MD(β=0.269,P=0.033,β=-0.364,P=0.003,respectively).Conclusions Left ventricular pressure-strain loop can reflect left ventricular systolic function and synchrony with good repeatability.which has potential clinical application value.

关 键 词：心肌做功 压力-应变环 超声心动图 心室功能 左 

分 类 号：R540.45[医药卫生—心血管疾病]