胎儿心外膜脂肪组织厚度与巨大儿的相关性研究  

Correlation Between Fetal Epicardial Fat Tissue Thickness and Macrosomia

作　　者：于妲 王子荣[2] 何吉庆[3] 郑哲岚[1] Yu Da;Wang Zirong;He Jiqing;Zheng Zhelan(Echocardiography and Vascular Ultrasound Center,The First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou,Zhejiang 310003,China;Department of Medical Imaging,The Affiliated Hospital of Hangzhou Normal University,Hangzhou,Zhejiang 310015,China;Department of Gynecology and Obstetrics,The Affiliated Hospital of Hangzhou Normal University,Hangzhou,Zhejiang 310015,China)

机构地区：[1]浙江大学医学院附属第一医院心血管超声中心,杭州市310003 [2]杭州师范大学附属医院医学影像科,杭州市310015 [3]杭州师范大学附属医院妇产科,杭州市310015

出　　处：《中国超声医学杂志》2021年第6期674-678,共5页Chinese Journal of Ultrasound in Medicine

基　　金：浙江省医药卫生科技计划项目(No.2020KY712)。

摘　　要：目的探讨超声测量胎儿心外膜脂肪组织厚度(EFT)与巨大儿的相关性。方法选取120例单胎妊娠孕妇作为研究对象,根据新生儿出生质量分为巨大儿组和对照组各60例。应用2D经腹超声测量胎儿双顶径、腹围、股骨长径、羊水指数及EFT,进行统计分析。结果巨大儿组胎儿EFT(1.43±0.18)mm大于对照组,差异有统计学意义(P<0.05)。多因素Logistic回归结果,胎儿EFT、胎儿腹围是巨大儿发生的独立危险因素(OR=8.14,95%CI 2.05~3.24,P<0.02;OR=2.07,95%CI 1.26~3.40,P<0.01);ROC曲线显示,胎儿EFT、胎儿腹围预测巨大儿发生的曲线下面积为0.827、0.892,最佳阈值为0.14 cm、35.45 cm,灵敏度和特异度为66.7%、85.0%,76.7%、98.3%;Pearson相关分析,胎儿EFT与胎儿腹围显著正相关(r=0.639,P<0.01)。结论超声测量胎儿EFT与孕妇分娩巨大儿显著相关,是巨大儿发生的独立危险因素之一,对预测巨大儿的发生具有临床意义。Objective Exploring the correlation between ultrasound measurement of fetal epicardial fat tissue thickness(EFT) and macrosomia. Methods A total of 120 singleton pregnancies were selected as the research objects. According to the birth weight of the newborns, they were divided into a macrosomia group 60 cases and a control group 60 cases. 2 D transabdominal ultrasound was used to measure fetal double parietal diameter, abdominal circumference, femoral long diameter, amniotic fluid index and EFT for statistical analysis. Results The fetal EFT(1.43±0.18)mm of the macrosomia group was greater than that of the control group, and the difference was statistically significant(P<0.05). Multivariate logistic regression results showed that fetal EFT and fetal abdominal circumference were independent risk factors for macrosomia(OR=8.14, 95%CI 2.05~3.24, P<0.02;OR=2.07, 95%CI 1.26~3.40, P<0.01);The ROC curve shows that the area under the curve for fetal EFT and fetal abdominal circumference to predict the occurrence of macrosomia is 0.827, 0.892, the best threshold is 0.14 cm, 35.45 cm, the sensitivity and specificity are 66.7%, 85.0%;76.7%, 98.3%;Pearson correlation analysis results showed that fetal EFT was significantly positively correlated with fetal abdominal circumference(r=0.639, P<0.01). Conclusions Ultrasound measurement of fetal EFT is significantly related to maternal delivery of macrosomia. It is one of the independent risk factors for the occurrence of giant babies and has clinical significance in predicting the occurrence of macrosomia.

关 键 词：胎儿 心外膜脂肪厚度 2D经腹超声 巨大儿 

分 类 号：R714.5[医药卫生—妇产科学] R445.1[医药卫生—临床医学]