针刺改善278例餐后不适综合征患者消化不良相关症状:一项多中心随机对照研究的二次分析  

Improvement in dyspepsia related symptoms treated with acupuncture in 278 patients with postprandial distress syndrome:a secondary analysis of a multi-center randomized controlled trial

作　　者：王宇 杨静雯 胡慧[3] 王军[4] 赵静洁[5] 周炜[6] 齐翎羽 王丽琼[1,2] 石广霞 刘存志 WANG Yu;YANG Jing-wen;HU Hui;WANG Jun;ZHAO Jing-jie;ZHOU Wei;QI Ling-yu;WANG Li-qiong;SHI Guang-xia;LIU Cun-zhi(International Acupuncture and Moxibustion Innovation Institute,Beijing University of CM,Beijing 100029,China;School of Acupuncture-Moxibustion and Tuina,Beijing University of CM,Beijing 100029;Department of Acupuncture and Moxibustion,Dongfang Hospital,Beijing University of CM;Department of Acupuncture and Moxibustion,Dongzhimen Hospital,Beijing University of CM;Department of TCM,Beijing Friendship Hospital,Capital Medical University;Department of Acupuncture and Moxibustion,Huguosi Hospital of CM,Beijing University of CM)

机构地区：[1]北京中医药大学国际针灸创新研究院,北京100029 [2]北京中医药大学针灸推拿学院,北京100029 [3]北京中医药大学东方医院针灸科 [4]北京中医药大学东直门医院针灸科 [5]首都医科大学附属北京友谊医院中医科 [6]北京中医药大学附属护国寺中医医院针灸科

出　　处：《中国针灸》2021年第6期583-587,共5页Chinese Acupuncture & Moxibustion

基　　金：北京市科技计划项目:Z161100000516007。

摘　　要：目的:评价针刺改善餐后不适综合征不同消化不良症状的临床疗效。方法:对一项多中心、随机对照试验数据进行二次分析。将278例餐后不适综合征患者随机分为针刺组(138例)和假针组(140例)。针刺组采用针刺百会、膻中、中脘、气海、内关、足三里等治疗。假针组选取6处非经非穴点进行浅刺。两组患者均每次治疗20 min,每周治疗3次,共治疗4周,随访12周。比较两组治疗前、治疗期间(第1、2、3、4周)及随访时(第8、12、16周)消化不良症状评分。结果:除第1周假针组的早饱感及呕吐症状外,治疗及随访期间两组消化不良症状评分均较治疗前降低(P<0.05)。治疗第2、3周,针刺组早饱感评分低于假针组(P<0.05);治疗第3周,针刺组餐后饱胀、上腹胀和嗳气症状评分低于假针组(P<0.05);治疗第4周及随访期间,针刺组餐后饱胀、早饱感、上腹胀和嗳气症状评分均低于假针组(P<0.05)。结论:针刺可显著改善餐后不适综合征患者餐后饱胀、早饱感、上腹胀和嗳气症状。Objective To evaluate the clinical effect of acupuncture for the improvements in various dyspeptic symptoms of postprandial distress syndrome.Methods The secondary analysis on the data of a multi-center randomized controlled trial(RCT)was conducted.278 patients with postprandial distress syndrome were randomized into an acupuncture group(138 cases)and a sham-acupuncture group(140 cases).In the acupuncture group,acupuncture was applied to Baihui(GV 20),Danzhong(CV 17),Zhongwan(CV 12),Qihai(CV 6),Neiguan(PC 6),Zusanli(ST 36),etc.In the sham-acupuncture group,6 sites,neither located on meridians nor belonged to meridian acupoints,were selected and punctured shallowly.The duration of treatment was 20 min each time,3 times a week,for 4 weeks totally in the two groups.The follow-up visit lasted for 12 weeks.The scores of dyspeptic symptoms were compared between the two groups before treatment,during treatment(in week 1,2,3 and 4)and during follow-up(in week 8,12 and 16)separately.Results Besides the scores of early satiety and vomiting in the sham-acupuncture group in week 1,the scores of the other dyspepsia symptoms during treatment and follow-up were all reduced in the two groups as compared with those before treatment(P<0.05).In week 2 and 3,the score of early satiety in the acupuncture group was lower than that in the sham-acupuncture group(P<0.05).In week 3,the scores of postprandial fullness,upper abdominal bloating and belching in the acupuncture group were lower than those in the sham-acupuncture group(P<0.05).In week 4 and during follow-up,the scores of postprandial fullness,early satiety,upper abdominal bloating and belching in the acupuncture group were all lower than those in the sham-acupuncture group(P<0.05).Conclusion Acupuncture remarkably relieves postprandial fullness,early satiety,upper abdominal bloating and belching in patients with postprandial distress syndrome.

关 键 词：餐后不适综合征 功能性消化不良 针刺 老十针 随机对照试验 

分 类 号：R246.1[医药卫生—针灸推拿学]