以掌跖为首发部位的急性泛发性扁平苔藓  

Acute generalized lichen planus with palmoplantar as the initial site:a case report

作　　者：石滢[1] 李珊山[1] 李杨 于艳[1] SHI Ying;LI Shan-shan;LI Yang;YU Yan(Department of Dermatology,the First Hospital of Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学第一医院皮肤科,吉林长春130021

出　　处：《临床皮肤科杂志》2021年第6期348-350,共3页Journal of Clinical Dermatology

摘　　要：报告1例以掌跖为首发部位的急性泛发性扁平苔藓。患者男,42岁。双手和双足出现鳞屑性红斑伴瘙痒2个月,加重累及躯干和四肢1.5个月。皮肤科检查:双手掌及双足弓弥漫紫红色鳞屑性斑块,边界清楚,可见皲裂;躯干和四肢散在较多米粒至绿豆大紫红色扁平丘疹,表面覆少许鳞屑,可见Wickham纹;口唇干燥,呈紫红色,伴少许鳞屑,颊黏膜可见网状白色条纹。皮损组织病理检查:表皮角化过度,灶状角化不全,颗粒层楔形增厚,棘层增厚,基底细胞液化变性;真皮浅层淋巴细胞呈带状浸润。诊断:急性泛发性扁平苔藓。A case of acute generalized lichen planus with palmoplantar as the initial site is reported.A 42-year-old man presented with erythematous and scaly plaques on both palms and soles accompanied by itching for 2 months,which was aggravated with trunk and limbs involvement for 1.5 months.Physical examination showed well-demarcated,diffuse erythematous and scaly plaques on the palms and soles,and flat-topped,polygonal and purple-to-violaceous plaques with fine white lines called Wickham striae covering the trunk and lower extremities.The patient's lips were dry and purple,covered with scales.The buccal mucosa was reticulated with white streaks.Histopathological examination showed hyperperatosis and focal parakeratosis with wedge-shaped hypergranulosis,irregular acanthosis,liquefaction degeneration of the basal cell layer,and band-like superficial dermal lymphohistiocytic infiltration.The diagnosis of acute generalized lichen planus was made.

关 键 词：扁平苔藓 泛发性 急性 掌跖 

分 类 号：R751[医药卫生—皮肤病学与性病学]