补肾调肝合剂联合针刺改善排卵障碍性不孕症患者排卵及不良情绪状态的临床观察  

Clinical observation on Bushen Tiaogan Heji combined with acupuncture in improving ovulation and negative emotions of anovulatory infertility

作　　者：莫颖茵 沈瑞扬 陈谊明 沈坚华 谭桂云 Mo Yinying;Shen Ruiyang;Chen Yiming;Shen Jianhua;Tan Guiyun(Guangzhou Liwan District Hospital of Chinese Medicine,Guangzhou 510140,China)

机构地区：[1]广州市荔湾区中医医院,510140

出　　处：《国际医药卫生导报》2021年第12期1789-1792,共4页International Medicine and Health Guidance News

基　　金：广东省中医药局科研项目(20181211)。

摘　　要：目的观察补肾调肝合剂联合针灸对排卵障碍性不孕症患者的排卵及不良情绪的影响,为治疗排卵障碍性不孕症提供新的思路和方法。方法选择2018年1月至2019年3月在本院诊断为肾虚肝郁型排卵障碍性不孕症患者60例,采用简单随机化分组法分为两组,各30例。治疗组年龄(32.13±4.46)岁;对照组年龄(29.97±5.10)岁。治疗组采用补肾调肝合剂联合针刺进行治疗,对照组采用克罗米芬促排卵并指导同房治疗。观察比较两组排卵周期率、妊娠率、中医证候评分、焦虑自评量表(SAS)和抑郁自评量表(SDS)评分情况。结果治疗组总治疗周期156个,排卵周期113个,排卵率为72.44%(113/156),平均排卵周期3.77个,妊娠率为46.67%(14/30)。对照组总治疗周期155个,排卵周期135个,排卵率为87.10%(135/155),平均排卵周期4.50个,妊娠率为33.33%(10/30)。治疗组1-3月、4-6月排卵率、妊娠率及总妊娠率均较对照组高,但差异均无统计学意义(均P>0.05);对照组总排卵率较治疗组高,差异有统计学意义(P<0.05)。治疗后,治疗组中医证候评分及SAS、SDS评分分别为(18.40±8.80)分、(36.86±5.53)分、(35.80±6.82)分,均低于对照组(38.30±8.83)分、(39.43±7.75)分、(38.86±7.35)分,差异均有统计学意义(均P<0.05)。结论补肾调肝合剂结合针刺治疗排卵障碍性不孕症能获得较高的临床妊娠率,且本法从整体出发,多方法、多靶点进行整体调理,明显改善患者焦虑、抑郁等不良情绪。Objective To observe the effects of Bushen Tiaogan Heji combined with acupuncture on the ovulation and negative emotions of patients with anovulatory infertility,so as to provide new ideas and methods for the treatment of anovulatory infertility.Methods Sixty kidney-deficiency and liver-depression type anovulatory infertility treated in our hospital from January 2018 to March 2019 were selected and were simply randomly divided into two groups,30 cases in each group.The age of the treatment group was(32.13±4.46)years old,and the age of the control group was(29.97±5.10)years old.The treatment group was treated with Bushen Tiaogan Heji combined with acupuncture,and the control group was given clomiphene for ovulation induction and sex guidance.The ovulation cycle rate,pregnancy rate,and the scores of TCM syndrome,Self-rating Anxiety Scale(SAS),and Self-rating Depression Scale(SDS)were compared between the two groups.Results In the treatment group,there were 156 treatment cycles,113 ovulation cycles,the ovulation rate was 72.44%(113/156),the mean ovulation cycle was 3.77 cycles,and the pregnancy rate was 46.67%(14/30).In the control group,there were 155 treatment cycles,135 ovulation cycles,the ovulation rate was 87.10%(135/155),the mean ovulation cycle was 4.50 cycles,and the pregnancy rate was 33.33%(10/30).The ovulation rate and pregnancy rate from January to March and from April to June and the total pregnancy rate in the treatment group were higher than those in the control group,but the differences were not statistically significant(all P>0.05).The total ovulation rate in the control groupwas higher than that in the treatment group,and the difference was statistically significant(P<0.05).After treatment,the TCM syndrome score,SAS score,and SDS score in the treatment group were(18.40±8.80),(36.86±5.53),and(35.80±6.82)points,respectively,which were lower than those in the control group[(38.30±8.83),(39.43±7.75),and(38.86±7.35)points],with statistically significant differences(all P<0.05).Conclusions Bushe

关 键 词：排卵障碍 补肾调肝合剂 针刺疗法 不良情绪 

分 类 号：R711.6[医药卫生—妇产科学]