血糖水平控制对经皮肾镜钬激光碎石术治疗糖尿病合并肾结石效果的影响  

Influence of blood glucose level control on effect of percutaneous nephrolithotomy with holmium laser lithotripsy in the treatment of diabetes complicated with kidney stones

作　　者：姚汝贺[1] 卢国汉[1] 李健辉[1] 陈文杰 叶志威 YAO Ruhe;LU Guohan;LI Jianhui;CHEN Wenjie;YE Zhiwei(Urology Surgery Department,New Rongqi Hospital,Foshan 528300,China)

机构地区：[1]广东省佛山市顺德区新容奇医院泌尿外科,广东佛山528300

出　　处：《临床医学研究与实践》2021年第18期87-90,共4页Clinical Research and Practice

摘　　要：目的探讨血糖水平控制对经皮肾镜钬激光碎石术治疗糖尿病合并肾结石效果的影响。方法选取本院收治的82例糖尿病合并肾结石行经皮肾镜钬激光碎石术的患者作为研究对象,根据术前血糖控制效果将其分为研究组(42例,血糖控制良好)和对照组(40例,血糖控制不佳)。比较两组的手术一般指标、血糖水平、血清炎症因子水平、术后并发症发生情况及复发率。结果两组的手术时间、手术成功率比较,差异无统计学意义(P>0.05);研究组的术后住院时间明显短于对照组(P<0.05)。两组术后2 h血糖水平均较术前明显增高,但研究组低于对照组(P<0.05)。两组术后2 h血清CRP、IL-6水平均较术前显著增高,并于术后1 d后显著降低,但仍比术前高(P<0.05);研究组术后2 h、术后1 d的血清CRP、IL-6水平均低于对照组(P<0.05)。两组并发症总发生率及术后6个月的复发率比较,差异无统计学意义(P>0.05);研究组术后12个月的复发率明显低于对照组(P<0.05)。结论血糖水平控制能促进糖尿病合并肾结石患者行经皮肾镜钬激光碎石术围术期的血糖稳定,减轻机体炎症状态,并降低远期复发率。Objective To investigate the influence of blood glucose level control on effect of percutaneous nephrolithotomy with holmium laser lithotripsy in the treatment of diabetes complicated with kidney stones.Methods A total of 82 patients with diabetes and kidney stones who underwent percutaneous nephrolithotomy with holmium laser lithotripsy admitted in our hospital were selected as the research objects.According to the effect of preoperative blood glucose control,the patients were divided into study group(42 cases,good blood glucose control)and the control group(40 cases,poor blood sugar control).The general surgical indexes,blood glucose level,serum inflammatory factor level,postoperative complications and recurrence rate were compared between the two groups.Results There were no significant differences in operation time and operation success rate between the two groups(P>0.05);the postoperative hospital stay in the study group was significantly shorter than that in the control group(P<0.05).The blood glucose level at 2 h after the operation in the two groups were significantly higher than that in the before operation,but that in the study group was lower than the control group(P<0.05).The levels of serum CRP and IL-6 in the two groups at 2 h after the operation were significantly higher than those before operation,and decreased significantly at 1 d after operation,but they were still higher than before operation(P<0.05);the levels of serum CRP and IL-6 in the study group at 2 h and 1 d after operation were lower than those in the control group(P<0.05).There were no statistically significant differences in the total incidence of complications and the recurrence rate at 6 months after the operation between the two groups(P>0.05);the recurrence rate in the study group at 12 months after operation was significantly lower than that in the control group(P<0.05).Conclusion Blood glucose level control can promote the perioperative blood glucose stabilization in patients with diabetes and kidney stones undergoing percutane

关 键 词：血糖水平 糖尿病 肾结石 经皮肾镜钬激光碎石术 

分 类 号：R587.1[医药卫生—内分泌]