生酮饮食抗炎作用机制研究进展  

Research progress of anti-inflammatory mechanism of ketogenic diet

作　　者：赵舒含 廖建湘[1] Zhao Shuhan;Liao Jianxiang(Department of Neurology,Shenzhen Children′s Hospital of China Medical University,Shenzhen 518038,Guangdong Pro-vince,China)

机构地区：[1]中国医科大学附属深圳市儿童医院神经内科,广东深圳518038

出　　处：《中华实用儿科临床杂志》2021年第11期873-875,共3页Chinese Journal of Applied Clinical Pediatrics

基　　金：深圳市医疗卫生三名工程 (SZSM201812005)。

摘　　要：生酮饮食是一种脂肪高比例,碳水化合物低比例,蛋白质和其他营养素合适的饮食结构,通过模拟饥饿状态,肝脏代谢脂肪酸产生酮体提供能量,并具有抗炎等作用。生酮饮食现已应用于神经系统疾病,但其作用机制尚不十分明确,现从生酮饮食抑制病原微生物,调整肠道菌群,减轻疼痛和通过多种途径减少氧化应激等方面,阐述其抗炎作用机制。Composed by high fat,low carbohydrate,adequate protein and other nutrients,ketogenic diet(KD)is a kind of diet.KD simulates starvation has fatty acid metabolism to produce ketone body,thus providing energy in liver,and it has various functions such as anti-inflammation.KD has been used in nervous system diseases,but its mechanism is still not very clear.As a result,the review expounds KD mechanism of anti-inflammatory action from the inhibition of pathogenic microorganisms,adjusting intestinal flora,relieving pain and reducing oxidative stress in several aspects.

关 键 词：生酮饮食 炎症 氧化应激 

分 类 号：R459.3[医药卫生—治疗学]