Mg-Ta_(2)O_(5)纳米棒涂层的制备、表征及其体外生物活性  

Preparation,Characterization and in Vitro Bioactivity of Mg-Ta_(2)O_(5) Nanorods

作　　者：王翠翠 童晨光 蔡安琦 张意茹 李新宇 郭宏伟[1] 殷海荣[1] Wang Cuicui;Tong Chenguang;Cai Anqi;Zhang Yiru;Li Xinyu;Guo Hongwei;Yin Hairong(School of Materials Science and Engineering,Shaanxi Key Laboratory of Green Preparation and Functionalization for Inorganic Materials,Shaanxi University of Science and Technology,Xi’an 710021,China)

机构地区：[1]陕西科技大学材料科学与工程学院,陕西省无机材料绿色制备与功能化重点实验室,陕西西安710021

出　　处：《稀有金属材料与工程》2021年第5期1753-1759,共7页Rare Metal Materials and Engineering

基　　金：国家自然科学青年科学基金(51801117);陕西省自然科学基金青年基金(2018JQ8008);西安市未央区科技计划(201706);陕西省国际科技合作计划(2018KW-030);陕西省重点研发计划(2017ZDXM-NY-048)。

摘　　要：采用两步水热处理的方法对钽进行表面改性,在其表面获得具有较小棒间距的掺镁氧化钽纳米棒阵列。通过改变镁元素的掺杂量,观察纳米棒形貌及微观结构的变化。在水热过程中,最佳的乙酸镁溶液浓度为0.05 mol/L,Mg在氧化钽纳米棒膜层中的含量达到4.25at%,以Mg^(2+)形式掺杂入Ta_(2)O_(5)纳米棒。使用AFM测量Ta、Ta_(2)O_(5)纳米棒和Mg-Ta_(2)O_(5)纳米棒样品的粗糙度,发现相比于纯钽片,Ta_(2)O_(5)纳米棒涂层和Mg-Ta_(2)O_(5)纳米棒涂层的粗糙度有所增加。ICP结果表明,生理盐水中镁离子的析出速率呈现先大幅度增加后变缓的趋势。在体外生物活性测试中,Ta_(2)O_(5)纳米棒涂层直到12 d后依然不能诱导出磷灰石;而Mg-Ta_(2)O_(5)纳米棒涂层表面不到8 d已经出现沉积磷灰石,Mg-Ta_(2)O_(5)纳米棒涂层有效地改善了钽基体表面的生物活性。Tantalum was modified by two-step hydrothermal treatment,and magnesium-doped tantalum oxide nanorods with narrow rod spacing were obtained on the surface of tantalum.The morphology and microstructure of nanorods were observed with the change of the doping amount of magnesium.In the process of hydrothermal treatment,the best concentration of magnesium acetate solution is 0.05 mol/L,and the content of Mg in tantalum oxide nanorods reaches 4.25 at%,and magnesium is doped in the form of Mg^(2+).The roughness was measured by AFM and the roughness of Ta_(2)O_(5)nanorods and Mg-Ta_(2)O_(5)nanorods is higher than that of pure tantalum.ICP results show that the precipitation rate of magnesium ions in normal saline increases greatly at first and then slows down.Ta_(2)O_(5)nanorod could not induce apatite until 12 d while apatite deposits on the surface of Mg-Ta_(2)O_(5)nanorod coating for less than 8 d in biological activity test.Mg-Ta_(2)O_(5)nanorod coating effectively improves the biological activity of tantalum substrate.

关 键 词：镁掺杂 氧化钽纳米棒 水热处理 生物活性 

分 类 号：TG174.4[金属学及工艺—金属表面处理]