脊椎动物胚胎期脊椎的形成及信号通路调控机制  

The Regulation Mechanism and Signal Pathway for Spine Formation in Vertebrate Embryo

作　　者：刘倩 岳静伟 牛乃琪 王立贤[1] 张龙超 LIU Qian;YUE Jingwei;NIU Naiqi;WANG Lixian;ZHANG Longchao(Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100193,China)

机构地区：[1]中国农业科学院北京畜牧兽医研究所,北京100193

出　　处：《畜牧兽医学报》2021年第6期1461-1470,共10页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：国家生猪产业技术体系(CARS-35);中国农业科学院科技创新工程(ASTIIP-IAS02)。

摘　　要：脊椎是哺乳动物整个躯体的支柱,具有较高的遗传力,且可对胴体长产生重要影响。不同物种之间的脊椎数量互不相同,甚至同一物种如猪、羊等物种内也存在变异。脊椎数主要受胚胎体节发育时期体节数量的影响,为了进一步探究脊椎形成和数量变异的调控机制,本文综述了脊椎的胚胎发育过程、重要中间结构体节的形成和调控因素,旨在阐明脊椎形成和发育的调控机制,进而为经济动物脊椎数的选育改良提供理论依据和研究思路。The spine is the backbone of the mammalian body which has high heritability and important impact on carcass length.Its number varies among species,even within the same species,such as pigs and sheep.The number of vertebra is affected by the number of somites during the embryo development.In order to further explore the regulation mechanism of spine formation and quantity variation,this article reviews the embryonic development process of the spine,the formation and regulation of important intermediate structural somites.The aim of this review is to clarify the regulation mechanism of spine formation and development and provide theoretical basis and ideas for number of vertebrae breeding in economic animals.

关 键 词：脊椎 胚胎发育 体节 信号通路 

分 类 号：S852.2[农业科学—基础兽医学]