Mapping Domain- and Age-Specific Functional Brain Activity for Children’s Cognitive and Affective Development  

作　　者：Lei Hao Lei Li Menglu Chen Jiahua Xu Min Jiang Yanpei Wang Linhua Jiang Xu Chen Jiang Qiu Shuping Tan Jia-Hong Gao Yong He Sha Tao Qi Dong Shaozheng Qin 

机构地区：[1]State Key Laboratory of Cognitive Neuroscience and Learning&IDG/McGovern Institute for Brain Research,Beijing Normal University,Beijing 100875,China [2]College of Teacher Education,Southwest University,Chongqing 400715,China [3]Key Laboratory of Beijing Key Laboratory of Brain Imaging and Connectomics,Beijing Normal University,Beijing 100875,China [4]School of Information Engineering,Huzhou University,Huzhou 313000,China [5]Key Laboratory of Cognition and Personality(SWU),Ministry of Education,Chongqing 400715,China [6]Faculty of Psychology,Southwest University,Chongqing 400715,China [7]Beijing HuiLongGuan Hospital,Peking University,Beijing 100096,China [8]Center for MRI Research,Academy for Advanced Interdisciplinary Studies,Peking University,Beijing 100871,China

出　　处：《Neuroscience Bulletin》2021年第6期763-776,共14页神经科学通报（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China(31522028,71834002,31530031,81571056,31521063,and 61775139);the Youth Science and Technology Innovation Program,Beijing Brain Initiative of Beijing Municipal Science and Technology Commission(Z181100001518003);the Open Research Fund of the State Key Laboratory of Cognitive Neuroscience and Learning(CNLZD1503 and CNLZD1703);the Fundamental Research Funds for the Central Universities.

摘　　要：The human brain undergoes rapid development during childhood,with significant improvement in a wide spectrum of cognitive and affective functions.Mapping domain-and age-specific brain activity patterns has important implications for characterizing the development of children’s cognitive and affective functions.The current mainstay of brain templates is primarily derived from structural magnetic resonance imaging(MRI),and thus is not ideal for mapping children’s cognitive and affective brain development.By integrating task-dependent functional MRI data from a large sample of 250 children(aged 7 to 12)across multiple domains and the latest easy-to-use and transparent preprocessing workflow,we here created a set of age-specific brain functional activity maps across four domains:attention,executive function,emotion,and risky decision-making.Moreover,we developed a toolbox named Developmental Brain Functional Activity maps across multiple domains that enables researchers to visualize and download domain-and age-specific brain activity maps for various needs.This toolbox and maps have been released on the Neuroimaging Informatics Tools and Resources Clearinghouse website(http://www.nitrc.org/projects/dbfa).Our study provides domain-and age-specific brain activity maps for future developmental neuroimaging studies in both healthy and clinical populations.

关 键 词：Brain activity maps FMRI COGNITION EMOTION REWARD Development 

分 类 号：R338[医药卫生—人体生理学]