泌尿外科下尿路结石患者感染状况及血清PCT水平研究  

Study on Infection Status and Serum PCT Level in Patients with Lower Urinary Tract Stones in Urology Department

作　　者：时适[1] SHI Shi(Department of Urology,Qiqihar First Hospital,Qiqihar,Heilongjiang Province,161000 China)

机构地区：[1]齐齐哈尔市第一医院泌尿外科,黑龙江齐齐哈尔161000

出　　处：《系统医学》2021年第7期103-105,共3页Systems Medicine

摘　　要：目的分析泌尿外科下尿路结石患者感染状况与血清PCT水平的变化。方法该次研究中的观察主体均随机抽选2017年5月—2019年12月时间段在该院泌尿外科接收的下尿路结石且出现感染的患者,将其作为观察组(n=52),并选择同时期接收的未出现感染的下尿路结石患者,将其作为对照组(n=52),比较两组患者的临床信息,分析影响患者尿路感染的因素和血清PCT水平变化。结果观察组患者63.5%结石直径≥2 cm,40.4%糖尿病,44.2%尿路梗阻,与对照组进行对比差异有统计学意义(χ^(2)=12.536,P<0.05;χ^(2)=4.514,P=0.034;χ^(2)=5.826,P=0.016);观察组患者治疗前血清PCT水平为(5.17±3.25)ng/L,明显高于对照组,差异有统计学意义(t=11.271,P<0.05);观察组52例患者经检测病原菌42株中革兰阴性菌66.7%,革兰阳性菌21.4%,真菌11.9%。结论泌尿外科下尿路结石患者出现感染的因素与其合并症、结石大小、尿路梗阻等相关,其血清PCT水平能够作为评估尿路感染的临床指标,对临床诊断与治疗具有重要价值。Objective To analyze the infection status and the changes of serum PCT levels in patients with lower urinary tract stones in urology department.Methods The subjects of observation in this study were randomly selected from May 2017 to December 2019 in patients with lower urinary tract stones and infections in the department of urology of the hospital.The number of patients was 52,and they were taken as observation group,and selected 52 patients with lower urinary tract stones who were not infected during the same period,as the control group;to compare the clinical information of the two groups of patients,and analyze the factors affecting the patients'urinary tract infection and the changes in serum PCT levels.Results 63.5%of patients in the observation group had calculus diameter≥2 cm,40.4%of diabetes,and 44.2%of urinary tract obstruction,which were statistically significant different from the control group(χ^(2)=12.536,P<0.05;χ^(2)=4.514,P=0.034;χ^(2)=5.826,P=0.016);the serum PCT level of patients in the observation group before treatment was(5.17±3.25)ng/L,which was significantly higher than that of the control group,the difference was statistically significant(t=11.271,P<0.05);52 patients in the observation group were tested with 42 pathogenic bacteria 66.7%of blue-negative bacteria,21.4%of gram-positive bacteria,and 11.9%of fungi.Conclusion The factors of infection in patients with lower urinary tract stones in urology surgery are related to their comorbidities,stone size,urinary tract obstruction,etc.The serum PCT level can be used as a clinical indicator to evaluate urinary tract infection,and has important value for clinical diagnosis and treatment.

关 键 词：血清PCT 泌尿外科 下尿路结石 尿路感染 合并症 

分 类 号：R59[医药卫生—内科学]