自动调节持续气道正压通气治疗阻塞性睡眠呼吸暂停的效果及对睡眠结构的影响  

Effect of Automatic Continuous Positive Airway Pressure on Obstructive Sleep Apnea and Its Influence on Sleep Structure

作　　者：徐彦飞 朱巧珍 徐晓妮 陈济明 杨远珠 XU Yanfei;ZHU Qiaozhen;XU Xiaoni;CHEN Jiming;YANG Yuanzhu(Xiehe Shenzhen Hospital of Huazhong University,Shenzhen 518000,China)

机构地区：[1]华中科技大学协和深圳医院,深圳518000

出　　处：《世界睡眠医学杂志》2021年第4期726-727,共2页World Journal of Sleep Medicine

基　　金：2019年深圳市南山区卫生健康局科研项目(2049010)。

摘　　要：目的:探析自动调节持续气道正压通气治疗阻塞性睡眠呼吸暂停的效果及对睡眠结构的影响。方法:选取2018年6月至2019年6月华中科技大学协和深圳医院收治的阻塞性睡眠呼吸暂停患者110例作为研究对象,按照治疗方法分为对照组和观察组,每组55例。对照组进行单水平固定压力持续气道正压通气(CPAP)治疗,观察组进行自动调节单水平持续气道正压通气(Auto-CPAP)治疗,分别评估2种治疗方式治疗效果及对睡眠结构的影响。结果:观察组治疗后睡眠呼吸暂停低通气指数(AHI)、最长呼吸暂停时间(LAT)明显低于对照组,同时血氧饱和度最小值(LSaO2)相较于对照组明显更高,差异有统计学意义(P<0.05);在睡眠结构上,观察组治疗后在N3-N4期以及快动眼睡眠期(REM)的占比,明显高于对照组,差异有统计学意义(P<0.05)。结论:阻塞性睡眠呼吸暂停患者采用自动调节单水平持续气道正压通气治疗,效果显著,患者睡眠质量显著提升且睡眠结构得到明显优化,具有推广应用意义。Objective:To explore the effect of automatic continuous positive airway pressure in the treatment of obstructive sleep apnea and its influence on sleep structure.Methods:A total of 110 patients with obstructive sleep apnea admitted to Xiehe Shenzhen Hospital of Huazhong University from June 2018 to June 2019 were selected as the research objects.According to the treatment method,they were divided into control group and observation group,55 cases in each group.The control group was treated with single level fixed pressure continuous positive airway pressure(CPAP),and the observation group was treated with auto regulated single level continuous positive airway pressure(auto-CPAP).The therapeutic effects of the two treatment methods and their effects on sleep structure were evaluated.Results:After treatment,sleep apnea hypopnea index(AHI)and the longest apnea time(LAT)in the observation group were significantly lower than those in the control group,and minimum blood oxygen saturation value(LSAO2)were significantly higher than those in the control group(P<0.05).In terms of sleep structure,the proportion of N3-N4 stage and rapid eye movement sleep(REM)in the observation group after treatment was significantly higher than that in the control group(P<0.05).Conclusion:Patients with obstructive sleep apnea were treated with automatic single level continuous positive airway pressure,the effect was significant,the sleep quality of patients was significantly improved,and the sleep structure was significantly optimized,which has the significance of popularization and application.

关 键 词：自动调节 睡眠结构 睡眠质量 

分 类 号：R338.63[医药卫生—人体生理学]