Disseminated cutaneous leishmaniasis due to Leishmania(Leishmania) amazonensis in human immunodeficiency virus(HIV)-infected patients: A report of two cases  

作　　者：Camila F Araújo Iara B N Oliveira Murilo B Silveira Fátima Ribeiro-Dias 

机构地区：[1]Hospital de Doenças Tropicais Doutor Anuar Auad,Goiânia,Goiás,Brazil [2]Laboratório de Imunidade Natural(LIN),Instituto de Patologia Tropical e Saúde Pública,Universidade Federal de Goiás,Goiânia,Goiás,Brazil

出　　处：《Asian Pacific Journal of Tropical Medicine》2021年第6期281-284,共4页亚太热带医药杂志（英文版）

基　　金：supported by Research Program for Sistema único de Saúde (SUS)/Brazilian Ministry of Healthy/Funda??o de AmparoàPesquisa do Estado de Goiás (FAPEG) grant No. 201.710.267.001.235。

摘　　要：Rationale: Co-infection of human immunodeficiency virus(HIV) and Leishmania spp. has impact on clinical and therapeutic outcomes of leishmaniases. Most studies do not present the identification of Leishmania species causing American tegumentary leishmaniasis in co-infections. In the Americas, Leishmania(L.) Viannia(V.) braziliensis and L.(V.) guyanensis have been identified. Patient concerns: In this study, two cases of American tegumentary leishmaniasis in patients infected with HIV are described. Patients presented several lesions with rapid dissemination and mucosal involvement. Diagnosis: Disseminated cutaneous leishmaniasis caused by L. amazonensis was identified by molecular test. Interventions: The patients were treated with conventional therapies for HIV infection and American tegumentary leishmaniasis. Outcomes: In co-infection, the clinical manifestations are atypical and the treatment response can be impaired. Lessons: These cases show that HIV infection impacts L. amazonensis infection and point to the relevance of identifying Leishmania species, which can lead to a better patient management.

关 键 词：Leishmania amazonensis HIV Disseminated cutaneous leishmaniasis Case report 

分 类 号：R512.91[医药卫生—内科学]