七氟烷与丙泊酚麻醉在老年肺癌手术中患者认知功能情况分析  

Analysis of Cognitive Function of Sevoflurane and Propofol Anesthesia in Elderly Patients Undergoing Surgery for Lung Cancer

作　　者：孟晓钟 李永强[2] MENG Xiao-zhong;LI Yong-qiang(Department of Anesthesiology,People’s Hospital of Yancheng District,Luohe,Henan,462300,China)

机构地区：[1]漯河市郾城区人民医院麻醉科,河南漯河462300 [2]漯河市中心医院麻醉科,河南漯河462300

出　　处：《黑龙江医学》2021年第11期1196-1198,共3页Heilongjiang Medical Journal

摘　　要：目的:探讨七氟烷与丙泊酚麻醉在老年肺癌手术中患者认知功能情况。方法:通过选取漯河市郾城区人民医院2019年3月—2020年3月收治的100例老年肺癌患者作为研究对象,并随机掷色子分成对照组与观察组,每组各50例。对照组给予七氟烷麻醉,观察组给予丙泊酚麻醉,比较两组麻醉效果。结果:对照组术后简易精神状态评价量表(MMSE)评分均低于观察组,观察组血清S100β蛋白水平低于对照组(P<0.05)。结论:七氟烷麻醉术后认知功能障碍的发生率低于丙泊酚麻醉,可在临床上进行推广应用。Objective:To investigate the cognitive function of sevoflurane and propofol anesthesia in elderly patients undergoing surgery for lung cancer.Methods:A total of 100 elderly patients with lung cancer admitted to the hospital from March 2019 to March 2020 were selected as study subjects,and randomly divided into control group and observation group,with 50 cases in each.Sevoflurane anesthesia was used in the control group and propofol anesthesia was used in the observation group.The anesthetic effect of the two groups was compared.Results:Postoperative Minmental State Examination(MMSE)score of the control group was lower than that of the observation group,and serum S100 protein level of the observation group was lower than that of the control group(P<0.05).Conclusion:The incidence of postoperative cognitive dysfunction of sevoflurane is lower than that of propofol,which can be popularized and applied in clinical practice.

关 键 词：七氟烷 丙泊酚 麻醉 

分 类 号：R971.2[医药卫生—药品]