桂枝新加汤治疗神经根型颈椎病营血虚证临床研究  

Clinical Study on Guizhi Xinjia Tang for Cervical Spondylotic Radiculopathy with Deficiency of Nutrient and Blood Syndrome

作　　者：王浩翔 杨雷 梁薛辰 李兆勇 贺美宇 巴玉琛 杨少锋[3] WANG Haoxiang;YANG Lei;LIANG Xuechen;LI Zhaoyong;HE Meiyu;BA Yuchen;YANG Shaofeng

机构地区：[1]开封市中医院,河南开封475000 [2]湖南中医药大学,湖南长沙410000 [3]湖南中医药大学第一附属医院,湖南长沙410007

出　　处：《新中医》2021年第11期18-22,共5页New Chinese Medicine

基　　金：长沙市科技计划项目(kq1907037)。

摘　　要：目的:观察桂枝新加汤治疗神经根型颈椎病营血虚证的临床疗效。方法:将收治的60例神经根型颈椎病患者随机分为2组各30例。对照组口服塞来昔布胶囊加甲钴胺片,观察组予桂枝新加汤口服,疗程均为2周。在治疗前、治疗结束时及治疗结束后3个月随访,比较2组疼痛视觉评分法(VAS)评分及中医证候评分。结果:在改善VAS评分方面:治疗结束时,2组组内比较,差异均有统计学意义(P<0.05),组间比较,差异无统计学意义(P>0.05);治疗结束后3个月随访时与治疗结束时比较,观察组差异无统计学意义(P>0.05),对照组差异有统计学意义(P<0.05)。在改善中医证候评分方面:治疗结束时,2组组内比较,差异均有统计学意义(P<0.05);观察组积分改善优于对照组,差异有统计学意义(P<0.05);治疗结束后3个月随访时与治疗结束时比较,观察组差异无统计学意义(P>0.05),对照组差异有统计学意义(P<0.05)。临床疗效总有效率观察组83.3%,对照组76.7%,2组临床总有效率比较,差异无统计学意义(P>0.05)。结论:桂枝新加汤治疗神经根型颈椎病营血虚证临床疗效良好,且远期效果优于单纯采用西药治疗。Objective: To observe the clinical effect of Guizhi Xinjia tang for cervical spondylotic radiculopathy with deficiency of nutrient and blood syndrome. Methods:A total of 60 cases of patients with cervical spondylotic radiculopathy who were admitted and treated were randomly divided into two groups,30 cases in each group. The control group was given the oral administration of celecoxib capsules and mecobalamin tablets, and the observation group was given the oral administration of Guizhi Xinjia tang. Both groups were treated for two weeks. Before treatment,after treatment,and during the follow-up three months after treatment, the score of Visual Analogue Scale(VAS) for evaluating pain and Chinese medicine syndrome score were compared between the two groups. Results: After treatment, the comparison of improvement in VAS score within the group showed significance in differences(P<0.05);there was no significant difference being found in the comparison of the improvement between the two groups(P>0.05). In the observation group, when compared improvement in VAS score during the follow-up three months after treatment with that after treatment,there was no significance in the difference(P>0.05);in the control group,when compared the improvement between the two periods above, there was significance in the difference(P<0.05). After treatment, the comparison of improvement in Chinese medicine syndrome score within the group showed significance in differences(P<0.05);the improvement in the observation group was better than that in the control group,the difference being significant(P<0.05). In the observation group,when compared improvement in Chinese medicine syndrome score during the follow-up three months after treatment with that after treatment, there was no significance in the difference(P>0.05);in the control group, when compared the improvement between the two periods above,there was significance in the difference(P<0.05). The total effective rate of clinical effect was 83.3% in the observation group,and 76.7% in the

关 键 词：神经根型颈椎病 营血虚证 桂枝新加汤 疼痛 中医证候评分 

分 类 号：R681.5[医药卫生—骨科学]