中药汤剂联合鼻内镜下咽鼓管吹张治疗分泌性中耳炎患儿临床研究  

Clinical Study on Chinese Herbal Decoction Combined with Eustachian Tube Insufflation via Nasal Endoscopy for Children with Secretory Otitis Media

作　　者：孙秉奎 易欢欢 张可[1] 李檬[1] SUN Bingkui;YI Huanhuan;ZHANG Ke;LI Meng

机构地区：[1]郑州大学附属儿童医院耳鼻咽喉科,河南郑州450000

出　　处：《新中医》2021年第11期103-106,共4页New Chinese Medicine

摘　　要：目的:观察中药汤剂联合鼻内镜下咽鼓管吹张治疗分泌性中耳炎患儿的临床疗效。方法:选取82例分泌性中耳炎患儿进行回顾性分析,根据患儿采取的不同治疗方案将纳入研究的病例资料分为观察组和对照组。对照组行鼻内镜下咽鼓管吹张治疗,观察组在对照组基础上联合中药汤剂治疗。对比2组患儿1个月后复查时疗效情况、治疗期间不良反应发生情况及6个月随访期间内的复发情况,对比2组患儿治疗前和治疗1个月后的耳积液血小板活化因子(PAF)及内皮素-1 (ET-1)含量变化。结果:对照组治疗后总有效率为87.18%,观察组治疗后总有效率为97.67%,2组比较,差异有统计学意义(P<0.05)。与同组治疗前比较,2组治疗后PAF、ET-1含量均降低(P<0.05);与对照组治疗后比较,观察组PAF、ET-1含量均较低(P<0.05)。2组不良反应总发生率比较,差异无统计学意义(P>0.05)。与对照组比较,观察组复发率较低(P<0.05)。结论:中药汤剂联合鼻内镜下咽鼓管吹张治疗分泌性中耳炎患儿的临床疗效较好,可有效降低患儿炎症反应,且复发率低,治疗安全性较好。Objective: To observe the clinical effect of Chinese herbal decoction combined with eustachian tube insufflation via nasal endoscopy for children with secretory otitis media. Methods: A total of 82 cases of children with secretory otitis media were selected so as to conduct a retrospective analysis of medical records,and were divided into the observation group and the control group based on different treatment schemes. The control group was performed eustachian tube insufflation via nasal endoscopy,and the observation group was additionally given Chinese herbal decoction based on the treatment of the control group. In the reexamination one month after treatment, the curative effect was compared between the two groups. The incidence of adverse reactions during treatment was compared between the two groups. During the follow-up six months after treatment, the recurrence was compared between the two groups. Before treatment and after one-month treatment, changes in contents of platelet activating factor(PAF) and endothelin-1(ET-1) in ear effusion were compared between the two groups. Results:After treatment,the total effective rate was 87.18% in the control group and 97.67% in the observation group, the difference being significant(P<0.05). Compared with those in the same group before treatment, contents of PAF and ET-1 in the two groups were decreased after treatment(P<0.05). Compared with those in the control group after treatment,contents of PAF and ET-1 in the observation group were lower(P<0.05). There was no significant difference being found in the comparison of the total incidence of adverse reactions between the two groups(P>0.05). Compared with that in the control group,the recurrence rate in the observation group was lower(P<0.05).Conclusion:The therapy of Chinese herbal decoction combined with eustachian tube insufflation via nasal endoscopy has a good clinical effect in the treatment of children with secretory otitis media,which can effectively relieve their inflammatory responses,with low recurrence ra

关 键 词：分泌性中耳炎 鼻内镜下咽鼓管吹张治疗 中药汤剂 细菌学指标 复发率 

分 类 号：R276.1[医药卫生—中医五官科学] R764.21[医药卫生—中医学]