通瘀消炎汤联合常规医护措施治疗慢性前列腺炎临床研究  

Clinical Study on Tongyu Xiaoyan Tang Combined with Routine Medical Measures for Chronic Prostatitis

作　　者：胡琳琳 杨梅[1] 孙慧芳[1] HU Linlin;YANG Mei;SUN Huifang

机构地区：[1]杭州市中医院丁桥院区,浙江杭州310021

出　　处：《新中医》2021年第11期187-190,共4页New Chinese Medicine

摘　　要：目的:观察通瘀消炎汤联合常规医护措施治疗Ⅲ型慢性前列腺炎(CP)湿热瘀滞证的临床效果。方法:选取120例患者随机分为对照组和观察组各60例。2组均口服盐酸坦索罗辛缓释胶囊、前列倍喜胶囊,并给予心理护理、饮食指导、生活方式干预等综合护理措施。观察组加予通瘀消炎汤坐浴。2组均治疗6周。治疗前、治疗6周后评定2组患者的慢性前列腺炎症状指数(NIH-CPSI)评分、中医症状评分,检测前列腺液中的锌离子(Zn^(2+))、前列腺特异性抗原(PSA)水平。比较2组的疾病疗效和中医证候疗效。结果:治疗后,2组NIH-CPSI疼痛不适、排尿症状、生活质量3个因子的评分及总分均较治疗前下降(P<0.01),观察组3项评分及总分均低于对照组(P<0.01)。观察组疾病疗效与中医证候疗效均优于对照组,差异均有统计学意义(P<0.05)。2组前列腺液Zn^(2+)及PSA水平均较治疗前升高(P<0.01),观察组前列腺液Zn^(2+)及PSA水平均高于对照组(P<0.01)。结论:在常规医护措施基础上加用通瘀消炎汤坐浴治疗Ⅲ型CP湿热瘀滞证患者,可有效改善前列腺功能以及CP的临床症状,提高患者的生活质量。Objective:To observe the clinical effect of Tongyu Xiaoyan tang combined with routine medical measures for chronic prostatitis of type III with dampness-heat stasis syndrome. Methods:A total of 120 cases of patients were randomly divided into the control group and the observation group, 60 cases in each group. Both groups were given the oral administration of tamsulosin hydrochloride sustained release capsules and Qianlie Beixi capsules,as well as comprehensive nursing measures including psychological nursing, dietary guidance and lifestyle intervention;the observation group was additionally given sitz bath with Tongyu Xiaoyan tang.Both groups were treated for six weeks. Before treatment and after sixweek treatment, the scores of National Instituted of Health-Chronic Prostatitis Symptom Index(NIH-CPSI) and Chinese medicine symptoms in the two groups were assessed;the levels of zinc ions(Zn^(2+)) and prostate specific antigen(PSA) in prostatic fluid were examined. The curative effect of disease and Chinese medicine syndromes in the two groups were compared.Results:After treatment,the scores of pain and discomfort,voiding symptoms and quality of life in NIH-CPSI and the total scores in the two groups were decreased when compared with those before treatment(P<0.01);the above three scores and the total score in the observation group were lower than those in the control group(P<0.01).The curative effect of disease and Chinese medicine syndromes in the observation group was better than that in the control group,differences being significant(P<0.05).The levels of Zn^(2+) and PSA in prostatic fluid in the two groups were increased when compared with those before treatment(P<0.01),and the levels in the observation group were higher than those in the control group(P<0.01).Conclusion:Based on routine medical measures,the additional application of sitz bath with Tongyu Xiaoyan tang for patients with chronic prostatitis with dampness-heat stasis syndrome can improve the prostate function, clinical symptoms,and their quality o

关 键 词：慢性前列腺炎 湿热瘀滞证 通瘀消炎汤 中药坐浴 锌离子 前列腺特异性抗原 

分 类 号：R697.33[医药卫生—泌尿科学]