C-ROSE技术联合四维导航引导CT定位在经皮穿刺肺活检术中的应用  

Application of C-ROSE combined with 4D navigation-guided CT localization in percutaneous puncture lung biopsy

作　　者：张乐天[1] 陶磊[2] 王晓林 李星虹 王钧[1] 张莹[4] ZHANG Le-tian;TAO Lei;WANG Xiao-lin(Department of Respiratory Medicine,Hebei Provincial Chest Hospital,Shijiazhuang050041,China)

机构地区：[1]河北省胸科医院呼吸内科,河北石家庄050041 [2]河北省胸科医院结核五科,河北石家庄050041 [3]河北医科大学第二医院康复一科,河北石家庄050073 [4]河北省胸科医院放射科,河北石家庄050041

出　　处：《中国医学装备》2021年第6期99-102,共4页China Medical Equipment

基　　金：河北省2019年度医学科学研究课题计划(20190992)“ROSE联合四维导航引导CT穿刺活检术在肺部病变诊断的意义”。

摘　　要：目的:探讨快速现场细胞学评估(C-ROSE)技术联合四维导航引导CT定位在经皮穿刺肺活检术中的应用。方法:选取经手术病理确诊并行CT引导肺穿刺活检术的588例肺结节患者,将其分为采用C-ROSE联合四维导航引导CT肺穿刺活检术的联合组(138例)、四维导航引导CT肺穿刺活检术的四维组(150例)、常规CT引导肺穿刺活检术的常规组(150例)和C-ROSE指导常规引导肺穿刺活检术的C-ROSE组(150例)。根据穿刺情况评价疾病良恶性,采用四表格法分析不同穿刺活检术对肺结节良恶性的诊断结果,并进行比较。结果:联合组、四维组、常规组和C-ROSE组病理诊断结果评价良恶性病变的灵敏度分别为93.68%、82.61%、70.70%和74.19%,特异度分别为97.67%、86.21%、66.67%和61.40%,准确率分别为94.93%、84.00%、69.33%和69.33%;4组灵敏度、特异度和准确率比较差异有统计学意义(x^(2)=18.953,x^(2)=24.083,x^(2)=40.373;P<0.05)。结论:C-ROSE技术联合四维导航引导CT定位预测肺结节患者良恶性具有较高的诊断率,可为提早预测疾病类型提供参考。Objective:To explore the application value of cytological rapid on-site evaluation(C-ROSE)combined with computed tomography(CT)localization that was guided by four dimensional(4D)navigation in percutaneous puncture lung biopsy.Methods:588 patients with pulmonary nodules who were confirmed by surgical pathology and underwent CT-guided lung puncture biopsy were selected as the subjects,and they were divided into combination group(138 cases)that adopted C-ROSE combined with 4D navigation to guide CT for lung puncture biopsy,4D group(150 cases)that adopted 4D navigation to guide CT for lung puncture biopsy,conventional group(150 cases)that adopted conventional CT to guide lung puncture biopsy and C-ROSE group(150 cases)that adopted C-ROSE to guide conventional guidance for lung puncture biopsy.The benign and malignant situation of disease were evaluated according to puncture condition,and fourfold table method was adopted to analyze the diagnostic results of different puncture biopsies on benign and malignant lung nodules,and then the results among different methods were further compared.Results:The sensitivities of pathological diagnosis of combination group,4D group,conventional group and C-ROSE group were 93.68%,82.61%,70.70%and 74.19%,respectively.And the corresponding specificities of them were 97.67%,86.21%,66.67%and 61.40%,respectively.And the accuracies of them were 94.93%,84.00%,69.33%and 69.33%,respectively.In addition,the differences of sensitivity,specificity and accuracy among 4 groups were significant(x^(2)=18.953,x^(2)=24.083,x^(2)=40.373,P<0.05),respectively.Conclusions:C-ROSE technique combines with 4D navigation for guiding CT localization has higher diagnostic rate in predicting benign and malignant situation of patients with lung nodules,and it can provide reference for early prediction of the type of disease.

关 键 词：快速现场细胞学评估(C-ROSE) 四维导航 CT定位 经皮穿刺肺活检术 

分 类 号：R816.4[医药卫生—放射医学]