有机电致发光二极管在生物医学中的应用进展  

Organic Light-emitting Diode for Biomedicine

作　　者：郭璇 李步洪[1] GUO Xuan;LI Buhong(Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education,Fujian Provincial Key Laboratory of Photonics Technology,Fujian Normal University,Fuzhou 350007,China)

机构地区：[1]福建师范大学,医学光电科学与技术教育部重点实验室,福建省光子技术重点实验室,福州350007

出　　处：《激光生物学报》2021年第3期193-199,275,共8页Acta Laser Biology Sinica

基　　金：国家自然科学基金项目(61935004);福建省科技计划项目(2019Y4004)。

摘　　要：随着医疗光电产品的升级,人们对便携式医疗设备和全天候监测医学传感器的需求日益增大。得益于有机电致发光二极管(OLED)的柔性、可拉伸、轻薄、均匀辐照和贴合皮肤表面等优点,其正成为可穿戴式生物医学设备的新型光源。本文详细介绍了OLED在光动力疗法、光电容积脉搏监测、光吸收式血氧监测、光遗传学和光生物调制等领域的应用进展,充分展示了OLED在医疗光电产品中的应用潜力。为了满足临床应用对光源的需求,提高OLED发光功率及延长其寿命是未来的重要发展方向。The demand for portable medical equipment and all-day health monitor continues to increase with the development of the medical industry.Benefiting from the advantages such as flexibility,stretchability,light weight,uniform irradiation and jointing skin surface,organic light-emitting diodes(OLED)are becoming a new type of light source for wearable biomedical devices.In this review,recent advances of OLED in photodynamic therapy,photoplethysmography,oximeter,optogenetics,and photobiomodula-tion are summarized,and the potential application of OLED in wearable healthcare is highlighted.The future trends of OLED will be focused on the development of long-lived devices with high power density as the light sources for clinical applications.

关 键 词：有机电致发光二极管 光动力疗法 脉搏血氧仪 光遗传学 光生物调制 

分 类 号：R318.51[医药卫生—生物医学工程]